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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
Multimodality Imaging of Tumor Response to Doxil
TL;DR: It is essential to combine apoptosis imaging strategies with imaging of other critical biological or pathological pathways, such as metabolism and proliferation, to improve clinical decision making in apoptosis-related diseases and interventions.
Journal ArticleDOI
A new 18F-labeled BBN-RGD peptide heterodimer with a symmetric linker for prostate cancer imaging
Yongjun Yan,Yongjun Yan,Kai Chen,Min Yang,Xilin Sun,Xilin Sun,Shuanglong Liu,Xiaoyuan Chen,Xiaoyuan Chen +8 more
TL;DR: The use of a symmetric linker AEADP [AEADP = 3,3′-(2-aminoethylazanediyl)dipropanoic acid] for the synthesis of BBN-RGD peptide heterodimer shows comparable microPET imaging results with glutamate linked BBN -RGD heterodimers, indicating that the replacement of glutamate linker with AEadP linker did not affect the biological activities of BBn-R GD
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Pilot Prospective Evaluation of (18)F-Alfatide II for Detection of Skeletal Metastases.
TL;DR: 18F-Alfatide II PET/CT can be used to detect skeletal andBone marrow metastases, with nearly 100% sensitivity in osteolytic, mixed and bone marrow lesions.
Journal ArticleDOI
Automated radiochemical synthesis of [18F]FBEM: a thiol reactive synthon for radiofluorination of peptides and proteins.
TL;DR: The automated radiochemical synthesis of N-[2-(4-[(18)F]fluorobenzamido)ethyl]maleimide, a prosthetic group for radiolabeling the free sulfhydryl groups of peptides and proteins, is herein described.
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Conjugation of a Scintillator Complex and Gold Nanorods for Dual-Modal Image-Guided Photothermal and X-ray-Induced Photodynamic Therapy of Tumors.
Li Luo,Wenjing Sun,Yushuo Feng,Ruixue Qin,Jinghui Zhang,Dandan Ding,Tianhang Shi,Xiangmei Liu,Xiaoyuan Chen,Hongmin Chen +9 more
TL;DR: In vitro and in vivo studies demonstrated that the nanosensitizer offers good dual-modal imaging capability and significantly suppresses tumor progression under near-infrared light and X-ray irradiation.