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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
X-ray-Controlled Bilayer Permeability of Bionic Nanocapsules Stabilized by Nucleobase Pairing Interactions for Pulsatile Drug Delivery.
Hongzhang Deng,Hongzhang Deng,Lisen Lin,Sheng Wang,Guocan Yu,Zijian Zhou,Yijing Liu,Gang Niu,Jibin Song,Xiaoyuan Chen +9 more
TL;DR: These nanocapsules with tunable permeability show prolonged retention, remotely controlled drug release, enhanced targeted accumulation, and effective antitumor effects, indicating their potential as an anticancer drug delivery system.
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Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug-Resistant Cancer Cells.
Ruili Zhang,Shi Gao,Zhongliang Wang,Da Han,Lin Liu,Qingjie Ma,Weihong Tan,Jie Tian,Xiaoyuan Chen +8 more
TL;DR: The an anti‐MDR1 molecular beacon (MB)‐based micelle (a‐MBM) nanosystem is rationally designed and shows an efficient self‐delivery, enhanced enzymatic stability, excellent target selectivity, and high drug‐loading capacity.
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Differentiation of Reactive and Tumor Metastatic Lymph Nodes with Diffusion-weighted and SPIO-Enhanced MRI
TL;DR: Both diffusion-weighted and SPIO-enhanced MRI can distinguish tumor metastatic lymph nodes from reactive lymph nodes, however, neither method is able to detect tumor metastasis to the draining lymph nodes at early stages.
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Multi‐Responsive Bottlebrush‐Like Unimolecules Self‐Assembled Nano‐Riceball for Synergistic Sono‐Chemotherapy
Xiaoxiao Shi,Yang Zhang,Ye Tian,Shuyu Xu,En Ren,Shuang Bai,Xiaoyuan Chen,Chengchao Chu,Zhigang Xu,Gang Liu +9 more
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In vivo quantitative photoacoustic microscopy of gold nanostar kinetics in mouse organs
TL;DR: The experimental results showed that GNS accumulated significantly in both liver and spleen from blood circulation after administration, which was qualitatively validated by fluorescence imaging.