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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
Recent advances in biomaterial-boosted adoptive cell therapy.
TL;DR: A comprehensive summary of the latest progress in biomaterial-based strategies to enhance the efficacy of adoptive cell therapy, focusing on function-specific biomaterial design, is presented and the challenges and prospects of this field are discussed.
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Self-assembly of gold nanoparticles to silver microspheres as highly efficient 3D SERS substrates
Shouhui Chen,Shouhui Chen,Peng Huang,Zhihua Wang,Zhe Wang,Magdalena Swierczewska,Gang Niu,Daxiang Cui,Xiaoyuan Chen +8 more
TL;DR: A simple, one-pot, surfactant-free synthesis of 3D Ag microspheres (AgMSs) in aqueous phase at room temperature that acts as supports to fix the gold nanoparticles (GNPs) in 3D space via the interaction between the carboxyl groups of GNPs and the Ag atoms of AgMSs.
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Application of (99m)Technetium-HYNIC(tricine/TPPTS)-Aca-Bombesin(7-14) SPECT/CT in prostate cancer patients A first-in-man study
H. J. K. Ananias,Z. Yu,Hilde D. Hoving,Stefano Rosati,Rudi Dierckx,Fan Wang,Yongjun Yan,Xiaoyuan Chen,Jan Pruim,Jan Pruim,Marjolijn N. Lub-de Hooge,Wijnand Helfrich,Philip H. Elsinga,Igle J. de Jong +13 more
TL;DR: (99m)Tc-HABBN SPECT/CT for visualization of prostate cancer is safe but hampered by an unexpected low in vivo metabolic stability in man, which warrants further study of peptide-based radiopharmaceuticals.
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Potential Applications of Using 68Ga-Evans Blue PET/CT in the Evaluation of Lymphatic Disorder: Preliminary Observations
TL;DR: 68Ga-NEB PET/CT can be used as an alternative of 99mTc-SC lymphoscintigraphy in the evaluation of lymphatic disorders, which enables fast results and might be more accurate than the conventional 99m Tc- SC lymphoscintsigraphy.
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177Lu-EB-PSMA Radioligand Therapy with Escalating Doses in Patients with Metastatic Castration-Resistant Prostate Cancer
Jie Zang,Qingxing Liu,Huimin Sui,Rongxi Wang,Orit Jacobson,Xinrong Fan,Zhaohui Zhu,Xiaoyuan Chen +7 more
TL;DR: It is demonstrated that a 2.12-GBq dose of 177Lu-EB-PSMA seems to be safe and adequate in tumor treatment, and further investigations with an increased number of patients are warranted.