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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal Article
68Ga-NOTA-RM26 PET/CT in the Evaluation of Breast Cancer: A Pilot Prospective Study
TL;DR: The diagnostic accuracy of 68Ga-NOTA-RM26 PET/CT in breast cancer may correlate with ER expression and menstrual status of the patient, and it may be better to avoid performing this examination during the menstrual secretory phase to reduce physiological uptake in normal breast tissue.
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Positron emission tomography imaging of vascular endothelial growth factor receptor expression with (61)Cu-labeled lysine-tagged VEGF121.
Yin Zhang,Hao Hong,Gang Niu,Hector F. Valdovinos,Hakan Orbay,Tapas R. Nayak,Xiaoyuan Chen,Todd E. Barnhart,Weibo Cai +8 more
TL;DR: The use of (61)Cu as the radiolabel is desirable for small proteins such as K3-VEGF121, which has a much higher β(+) branching ratio than the commonly used (64)Cu, thereby offering stronger signal intensity and lower tracer dose for PET imaging.
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Stimuli-responsive size-changeable strategy for cancer theranostics
TL;DR: The latest progresses and biomedical applications ofsize-changeable theranostic nanoagents are systematically summarized and the perspectives and challenges of size- changeable strategy for cancer theranostics are discussed.
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Peptide Receptor Radionuclide Therapy of Late-Stage Neuroendocrine Tumor Patients with Multiple Cycles of 177Lu-DOTA-EB-TATE.
Qingxing Liu,Jie Zang,Huimin Sui,Jiakun Ren,Hua Guo,Hao Wang,Rongxi Wang,Orit Jacobson,Jingjing Zhang,Yuejuan Cheng,Zhaohui Zhu,Xiaoyuan Chen +11 more
TL;DR: Dose escalations of up to 3.97 GBq/cycle seem to be well tolerated for 177Lu-DOTA-EB-TATE, and the overall disease response rate and disease control rates were similar, according to the criteria of the European Organisation for Research and Treatment of Cancer.
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Enzyme-free colorimetric determination of EV71 virus using a 3D-MnO2-PEG nanoflower and 4-MBA-MA-AgNPs.
TL;DR: This enzyme-free immunoassay based on a hybrid 3D-MnO2 features signal amplification strategies via a simple reduction reaction, allowing a naked-eye detection limit of EV71 virus to be as low as 5 × 104 particles per mL, which is about three orders of magnitude lower than the conventional enzyme-linked immunosorbent assay (ELISA).