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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide.
TL;DR: Overall molecular charge and characteristics of Radiolabels have profound effects on tumor accumulation and in vivo kinetics of radiolabeled RGD peptide.
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Peptide-Based Probes for Targeted Molecular Imaging
Seulki Lee,Jin Xie,Xiaoyuan Chen +2 more
TL;DR: This review article examines the current trends in peptide-based imaging probes developed for in vivo applications and discusses the advantage of and challenges in developing peptides-based probes and summarizes current systems with respect to their unique design strategies and applications.
Journal ArticleDOI
Synthesizing and Dispersing Silver Nanoparticles in a Water-in-Supercritical Carbon Dioxide Microemulsion.
TL;DR: A method to synthesize and stabilize metallic silver nanoparticles having diameters from 5 to 15 nm in supercritical CO{sub 2} using an optically transparent, water-in-CO{ sub 2} microemulsion is described.
Journal Article
PET of Vascular Endothelial Growth Factor Receptor Expression
Weibo Cai,Kai Chen,Khalid A. Mohamedali,Qizhen Cao,Sanjiv S. Gambhir,Michael G. Rosenblum,Xiaoyuan Chen +6 more
TL;DR: Successful demonstration of the ability of (64)Cu-DOTA-VEGF(121) to visualize VEGFR expression in vivo may allow for clinical translation of this radiopharmaceutical for imaging tumor angiogenesis and guiding antiangiogenic treatment, especially patient selection and treatment monitoring of VEG FR-targeted cancer therapy.
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Co₉ Se₈ nanoplates as a new theranostic platform for photoacoustic/magnetic resonance dual-modal-imaging-guided chemo-photothermal combination therapy.
Xiaorong Song,Xiaoyong Wang,Shu-Xian Yu,Jianbo Cao,Shihua Li,Juan Li,Gang Liu,Huanghao Yang,Xiaoyuan Chen +8 more
TL;DR: The new theranostic platform based on biocompatible poly(acrylic acid) (PAA)-Co9 Se8 nanoplates shows pH-responsive chemotherapy and enables the combination of photothermal therapy and chemotherapy to receive superior antitumor efficacy.