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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
Gold Nanoparticle Coated Carbon Nanotube Ring with Enhanced Raman Scattering and Photothermal Conversion Property for Theranostic Applications
Jibin Song,Feng Wang,Xiangyu Yang,Bo Ning,Mary G. Harp,Stephen H. Culp,Song Hu,Peng Huang,Liming Nie,Jingyi Chen,Xiaoyuan Chen +10 more
TL;DR: A new type of carbon nanotube ring coated with gold nanoparticles (CNTR@AuNPs) using CNTR as a template and surface attached redox-active polymer as a reducing agent that was successfully employed for imaging and imaging-guided cancer therapy in two tumor xenograft models.
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68Ga-labeled multimeric RGD peptides for microPET imaging of integrin αvβ3 expression
Zibo Li,Kai Chen,Xiaoyuan Chen +2 more
TL;DR: The dimeric RGD peptide tracer 68Ga-NOTA–RGD2 with good tumor uptake and favorable pharmacokinetics warrants further investigation for potential clinical translation to image integrin αvβ3.
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Nanotechnology-Enhanced No-Wash Biosensors for in Vitro Diagnostics of Cancer.
TL;DR: This review provides a comprehensive overview of various nanomaterial-enhanced no-wash biosensing technologies and focuses on the analysis of the underlying mechanism of these technologies applied for the early detection of cancer biomarkers ranging from small molecules to proteins, and even whole cancerous cells.
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Antitumor Activity of a Unique Polymer That Incorporates a Fluorescent Self-Assembled Metallacycle
Guocan Yu,Mingming Zhang,Manik Lal Saha,Zhengwei Mao,Jin Chen,Yong Yao,Zijian Zhou,Yijing Liu,Changyou Gao,Feihe Huang,Xiaoyuan Chen,Peter J. Stang +11 more
TL;DR: The synthesis of a four-armed amphiphilic copolymer, Pt-PAZMB-b-POEGMA, containing a metallacycle M, in which the tetraphenylethene derivative acts as an aggregation-induced emissive fluorescent probe for live cell imaging and the 3,6-bis[trans-Pt(PEt3)2]phenanthrene (PhenPt) is an anticancer drug is reported on.
Journal ArticleDOI
Imaging of integrins as biomarkers for tumor angiogenesis.
Weibo Cai,Gang Niu,Xiaoyuan Chen +2 more
TL;DR: This review article will summarize the current state-of-the-art of imaging integrin expression using either single molecular imaging modality or a combination of different modalities.