Xiaoyuan Chen

TL;DR: Dimeric RGD peptide tracers with relatively high tumor integrin-specific accumulation and favorable in vivo kinetics may have the potential to be translated into clinic for integrin αvβ3 imaging.

TL;DR: Mild hyperthermia induced by laser-irradiated CuS nanoparticles can dramatically improve the cell uptake of nanotheranostics both in vitro and in–vivo, thus significantly enhancing the chemotherapeutic efficacy for complete tumor growth suppression without recurrence.

TL;DR: A new CDT strategy that uses intracellular labile iron pool (LIP) as the endogenous source of Fenton-reactive metals for eliciting free radical generation, and the discovery of hydroperoxides (R'OOH) as an optimal LIP-mediated chemodynamic agent against cancer is presented.

TL;DR: A comprehensive review on the synthesis and properties of polyphenol-containing nanoparticles is provided in this article, where the remarkable versatility of poly phenolic hydroxyl group-containing organic molecules in different biomedical applications including biodetection, multimodal bioimaging, protein and gene delivery, bone repair, antibiosis, and cancer theranostics is also demonstrated.

TL;DR: In vitro and in vivo study showed the affibody-based nanoprobes specifically target and image human epidermal growth factor receptor type 2 (HER2)-expressing cells and tumors.