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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
Long-Acting Release Formulation of Exendin-4 Based on Biomimetic Mineralization for Type 2 Diabetes Therapy.
TL;DR: A potent long-acting release system based on biomimetic mineralization was constructed for biocompatible and sustained exendin-4 delivery and can serve as a promising candidate for future clinical applications for type 2 diabetes therapies.
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Preclinical lymphatic imaging
TL;DR: In this review, a comprehensive summary of in vivo imaging modalities for detecting lymphatic vessels, lymphatic drainage, and lymphatic nodes are provided, which include conventional lymphatic imaging techniques such as dyes and radionuclide scintigraphy as well as novel techniques for lymphatic Imaging using lymphatic biomarkers, photoacoustic imaging, and combinations of multiple modalities.
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Magnetic/Fluorescent Barcodes Based on Cadmium-Free Near-Infrared-Emitting Quantum Dots for Multiplexed Detection
TL;DR: In this article, a single-wavelength encoding combined with size encoding is used to produce different optical codes by simply changing the wavelength and the intensity of the QDs as well as the size of the barcode microspheres.
Journal ArticleDOI
Rapid and Simple One-Step F-18 Labeling of Peptides
Orit Jacobson,Lei Zhu,Lei Zhu,Ying Ma,Ido D. Weiss,Xilin Sun,Gang Niu,Dale O. Kiesewetter,Xiaoyuan Chen +8 more
TL;DR: A novel one-step ¹⁸F radiolabeling strategy for peptides that contain a specific arene group is developed, which shortens reaction time and labor significantly, requires low amount of precursor, and results in specific activity of 79 ± 13 GBq/μmol.
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Single Low-Dose Injection of Evans Blue Modified PSMA-617 Radioligand Therapy Eliminates Prostate-Specific Membrane Antigen Positive Tumors
Zhantong Wang,Rui Tian,Gang Niu,Ying Ma,Lixin Lang,Lawrence P. Szajek,Dale O. Kiesewetter,Orit Jacobson,Xiaoyuan Chen +8 more
TL;DR: The construct described here, EB-PSMA-617, may improve the radiotherapeutic efficacy for patients with PSMA-positive tumors by reducing both the amount of activity needed for therapy as well as the frequency of administration, as compared to PSma-617.