X
Xiaoyun Dai
Researcher at Yale University
Publications - 30
Citations - 2934
Xiaoyun Dai is an academic researcher from Yale University. The author has contributed to research in topics: Cancer & STAT3. The author has an hindex of 18, co-authored 28 publications receiving 2145 citations. Previous affiliations of Xiaoyun Dai include National University of Singapore & Sichuan University.
Papers
More filters
Journal ArticleDOI
Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.
Kodappully Sivaraman Siveen,Sakshi Sikka,Rohit Surana,Xiaoyun Dai,Jingwen Zhang,Alan Prem Kumar,B. K. H. Tan,Gautam Sethi,Anupam Bishayee +8 more
TL;DR: The evidence for critical roles ofSTAT3 in oncogenesis is presented and the potential for development of novel cancer therapies based on mechanistic understanding of STAT3 signaling cascade is discussed.
Journal ArticleDOI
Ageing and the telomere connection: An intimate relationship with inflammation.
Jingwen Zhang,Grishma Rane,Xiaoyun Dai,Muthu K. Shanmugam,Frank Arfuso,Ramar Perumal Samy,Mitchell K.P. Lai,Dennis Kappei,Alan Prem Kumar,Gautam Sethi +9 more
TL;DR: The intricate association between the various inflammatory molecules and telomeres that together contribute to the ageing process and related diseases are summarized.
Journal ArticleDOI
Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies
TL;DR: This review not only summarizes the diverse molecular targets of ursolic acid, but also provides an insight into the various preclinical and clinical studies that have been performed in the last decade with this promising triterpenoid.
Journal ArticleDOI
Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma.
Aruljothi Subramaniam,Muthu K. Shanmugam,Ekambaram Perumal,Feng Li,Alamelu Nachiyappan,Xiaoyun Dai,Shivananju Nanjunda Swamy,Kwang Seok Ahn,Alan Prem Kumar,B. K. H. Tan,Kam M. Hui,Gautam Sethi +11 more
TL;DR: The possible role of STAT3 signaling cascade and its interacting partners in the initiation of HCC is discussed and the role of various STAT3 regulated genes in HCC progression, inflammation, survival, invasion and angiogenesis is analyzed.
Journal ArticleDOI
Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: Preclinical and clinical evidence
TL;DR: This review summarizes the diverse molecular targets of OA and its derivatives and also provides clear evidence on their promising potential in preclinical and clinical situations.