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Xing Yu
Researcher at Hong Kong Baptist University
Publications - 3
Citations - 175
Xing Yu is an academic researcher from Hong Kong Baptist University. The author has contributed to research in topics: Autophagy & TFEB. The author has an hindex of 2, co-authored 3 publications receiving 96 citations.
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Journal ArticleDOI
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition
Ju-Xian Song,Yueru Sun,Ivana Peluso,Yu Zeng,Xing Yu,Jia-Hong Lu,Zheng Xu,Mingzhong Wang,Liang-Feng Liu,Yingyu Huang,Lei-Lei Chen,Siva Sundara Kumar Durairajan,Hongjie Zhang,Bo Zhou,Hong Qi Zhang,Aiping Lu,Andrea Ballabio,Diego L. Medina,Zhihong Guo,Min Li +19 more
TL;DR: Curcumin derivative C1 is identified as a novel MTOR-independent activator of TFEB, which enhances autophagy and lysosome biogenesis in vitro and in vivo and is a potential therapeutic agent for the treatment of neurodegenerative diseases.
Journal ArticleDOI
Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson's Disease.
Lei-Lei Chen,Yujv Huang,Xing Yu,Jia-Hong Lu,Wenting Jia,Ju-Xian Song,Ju-Xian Song,Liang-Feng Liu,Youcui Wang,Yingyu Huang,Junxia Xie,Min Li +11 more
TL;DR: In this article, the authors used Corynoxine (Cory), an oxindole alkaloid isolated from the Chinese herbal medicine Uncaria rhynchophylla (Miq.) Jacks, as a new autophagy enhancer that promoted the degradation of α-synuclein in a PD cell model.