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Xinhui Wang
Researcher at Harvard University
Publications - 3
Citations - 344
Xinhui Wang is an academic researcher from Harvard University. The author has contributed to research in topics: Ovarian cancer & Antigen. The author has an hindex of 3, co-authored 3 publications receiving 290 citations.
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Journal ArticleDOI
Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism
Jianqun Liao,Feng Qian,Nana Tchabo,Paulette Mhawech-Fauceglia,Amy Beck,Zikun Qian,Xinhui Wang,Wendy J. Huss,Shashikant Lele,Carl Morrison,Kunle Odunsi +10 more
TL;DR: In insight into the relationship between tumor dissemination and metabolic attributes of human cancer stem cells, spheroid cells were found to be enriched for cells with cancer stem cell-like characteristics and contributed to tumor generation, progression and chemotherapy resistance.
Journal ArticleDOI
Characterization of a Putative Ovarian Oncogene, Elongation Factor 1α, Isolated by Panning a Synthetic Phage Display Single-Chain Variable Fragment Library with Cultured Human Ovarian Cancer Cells
Sameer Sharma,Jonathan Tammela,Xinhui Wang,Hilal Arnouk,Deborah L. Driscoll,Paulette Mhawech-Fauceglia,Shashikant Lele,A. Latif Kazim,Kunle Odunsi +8 more
TL;DR: It is proposed that EEF1A2, a highly homologous and functionally similar oncogene, was found to be restricted only to the normal tissues of the heart, brain, and skeletal muscle, and may be a useful target for therapy of human ovarian cancer.
Journal ArticleDOI
Development of a Reactive Stroma Associated with Prostatic Intraepithelial Neoplasia in EAF2 Deficient Mice
Laura E. Pascal,Junkui Ai,Khalid Z. Masoodi,Yujuan Wang,Dan Wang,Kurtis Eisermann,Lora H. Rigatti,Katherine J. O’Malley,Hei M. Ma,Xinhui Wang,Javid A. Dar,Anil V. Parwani,Brian W. Simons,Michael Ittman,Luyuan Li,Benjamin Davies,Zhou Wang +16 more
TL;DR: It is suggested that the EAF2 knockout mouse on the C57BL/6J and FVB/NJ genetic backgrounds provides a model of PIN lesions associated with an altered prostate microvasculature and reactive stromal compartment corresponding to that reported in human prostate tumors.