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Xu-Hong Yang

Bio: Xu-Hong Yang is an academic researcher. The author has contributed to research in topics: Aryl & Regioselectivity. The author has an hindex of 1, co-authored 2 publications receiving 27 citations.

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Journal ArticleDOI
TL;DR: The current review article will briefly outline the new routes and strategies for the synthesis of valuable 4(3H)-quinazolinones.
Abstract: The 4(3H)-quinazolinone is a frequently encountered heterocycle with broad applications including antimalarial, antitumor, anticonvulsant, fungicidal, antimicrobial, and anti-inflammatory. The current review article will briefly outline the new routes and strategies for the synthesis of valuable 4(3H)-quinazolinones.

176 citations

Journal ArticleDOI
TL;DR: Results indicate that novel arylimine derivatives containing the 4(3H)-quinazolinone moiety can effectively control tobacco bacterial wilt, tomato bacterial wilts, and X. oryzae.
Abstract: Twenty-seven novel (E)-3-[2-arylideneaminoethyl]-2-[4-(trifluoromethoxy)anilino]-4(3H)-quinazolinone derivatives were synthesized by reacting various aromatic aldehydes with intermediate 6. The target compounds were characterized by 1H NMR, 3C NMR, IR, and elemental analysis. Bioassay results revealed that some of the compounds have strong antifungal activities against six fungi (Gibberella zeae, Fusarium oxysporum, Clematis mandshurica, Paralepetopsis sasakii, Phytophthora infestans, and Sclerotinia sclerotiorum) and three bacteria (Xanthomonas oryzae, tomato bacterial wilt, and tobacco bacterial wilt). Notably, these compounds exhibited the highest activity against tomato bacterial wilt and X. oryzae, with 50% effective concentration (EC50) values ranging from 45.96 to 93.31 μg/mL and from 20.09 to 21.33 μg/mL, respectively, which are superior to those of the commercial antibacterial agents thiodiazole-copper (99.80 μg/mL) and bismerthiazol (92.61 μg/mL). These results indicate that novel arylimine deri...

96 citations

Journal ArticleDOI
Xiang Wang1, Juan Yin1, Li Shi1, Guoping Zhang1, Baoan Song1 
TL;DR: Results indicated that novel Schiff base derivatives containing the 4(3H)-quinazolinone moiety can effectively control tobacco and tomato bacterial wilts.

73 citations

Journal ArticleDOI
TL;DR: This review has outlined the extensive application of carbodiimides in the synthesis of N-heterocycles from the 1980s to today.
Abstract: Carbodiimides are a unique class of heterocumulene compounds that display distinctive chemical properties. The rich chemistry of carbodiimides has drawn increasing attention from chemists in recent years and has made them exceedingly useful compounds in modern organic chemistry, especially in the synthesis of N-heterocycles. This review has outlined the extensive application of carbodiimides in the synthesis of N-heterocycles from the 1980s to today. A wide range of reactions for the synthesis of various types of N-heterocyclic systems (three-, four-, five-, six-, seven-, larger-membered and fused heterocycles) have been developed on the basis of carbodiimides and their derivatives.

57 citations

Journal ArticleDOI
TL;DR: In this article, the iodine-catalyzed reaction of 2-aminobenzamides with 1,3-cyclohexanediones gave structurally diversified products.

28 citations