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Xuejun Jin
Researcher at Yanbian University
Publications - 86
Citations - 2111
Xuejun Jin is an academic researcher from Yanbian University. The author has contributed to research in topics: NF-κB & Kinase. The author has an hindex of 23, co-authored 79 publications receiving 1389 citations. Previous affiliations of Xuejun Jin include Korea Research Institute of Bioscience and Biotechnology.
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Journal ArticleDOI
A sensitive and selective fluorescent probe for cysteine based on a new response-assisted electrostatic attraction strategy: the role of spatial charge configuration.
TL;DR: The probe m-CP, a coumarin fluorophore conjugated with a substituted methyl pyridinium group through an unsaturated ketone unit, showed highly selective and sensitive detection for cysteine (Cys) over homocysteine(Hcy) and glutathione (GSH), and the practical utility of this probe in the fluorescent labeling of Cys residues within proteins was demonstrated.
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A cysteine probe with high selectivity and sensitivity promoted by response-assisted electrostatic attraction.
TL;DR: A new turn-on fluorescent probe for fast detection of cysteine in physiological conditions, based on a new response-assisted electrostatic attraction strategy, is reported.
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Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF-κB and TNF-α/TNFR1/NF-κB pathways.
Xiang Xu,Hu-Nan Piao,Fumie Aosai,Xiao-Yu Zeng,Jia-Hui Cheng,Yue-Xian Cui,Jing Li,Juan Ma,Hu-Ri Piao,Xuejun Jin,Lian Xun Piao +10 more
TL;DR: This study has investigated the antidepressant mechanism of arctigenin by conducting in vitro and in vivo studies, and found that proinflammatory cytokines in microglia via high‐mobility group box 1 (HMGB1)/TLR4/NF‐κB and TNF‐α/TNFR1/NF-κB signalling pathways, leading to depression.
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Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways.
Chunliu Mi,Juan Ma,Ke Si Wang,Hong Xiang Zuo,Zhe Wang,Ming Yue Li,Lian Xun Piao,Guang Hua Xu,Xuezheng Li,Zhe Shan Quan,Xuejun Jin +10 more
TL;DR: It is suggested that imperatorin is an effective inhibitor of HIF-1 and provide new perspectives into the mechanism of its anticancer activity.
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Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways.
Ke Si Wang,Junbo Li,Zhe Wang,Chunliu Mi,Juan Ma,Lian Xun Piao,Guang Hua Xu,Xuezheng Li,Xuejun Jin +8 more
TL;DR: The anti-inflammatory effects of artemisinin in TPA-induced skin inflammation in mice were demonstrated and it was proved that art Artemisinin potentiated TNF-α-induced apoptosis.