X
Xuekui Xia
Researcher at Qilu University of Technology
Publications - 170
Citations - 2583
Xuekui Xia is an academic researcher from Qilu University of Technology. The author has contributed to research in topics: Raw material & Sea cucumber. The author has an hindex of 21, co-authored 162 publications receiving 2072 citations. Previous affiliations of Xuekui Xia include Chinese Academy of Sciences & Sun Yat-sen University.
Papers
More filters
Journal ArticleDOI
A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules.
Mindong Liang,Mindong Liang,Zilong Li,Weishan Wang,Jiakun Liu,Jiakun Liu,Leshi Liu,Guoliang Zhu,Loganathan Karthik,Man Wang,Ke-Feng Wang,Zhong Wang,Jing Yu,Yuting Shuai,Jiaming Yu,Lu Zhang,Zhiheng Yang,Chuan Li,Qian Zhang,Tong Shi,Liming Zhou,Feng Xie,Huanqin Dai,Xueting Liu,Jie Zhang,Guang Liu,Ying Zhuo,Buchang Zhang,Chenli Liu,Shanshan Li,Xuekui Xia,Yaojun Tong,Yanwen Liu,Gil Alterovitz,Gao-Yi Tan,Lixin Zhang +35 more
TL;DR: CaT-SMelor is presented which uses Cas12a and allosteric transcription factors to detect small molecules in the nanomolar range and directly measured the uric acid concentration in clinical human blood samples, indicating a great potential of CaT- SMelor in the detection of small molecules.
Journal ArticleDOI
Antioxidant and antihyperlipidemic activities of polysaccharides from sea cucumber Apostichopus japonicus.
Xin Liu,Zhenliang Sun,Miansong Zhang,Xiumei Meng,Xuekui Xia,Wenpeng Yuan,Feng Xue,Changheng Liu +7 more
TL;DR: Results suggest that AJP may prove to be a potential candidate of the natural antioxidants as a therapeutic agent for hyperlipidemia.
Journal ArticleDOI
Chemistry and weak antimicrobial activities of phomopsins produced by mangrove endophytic fungus Phomopsis sp. ZSU-H76.
Zhongjing Huang,Xiaoling Cai,Chang-Lun Shao,Zhigang She,Xuekui Xia,Yiguang Chen,Jianxiang Yang,Shining Zhou,Yongcheng Lin +8 more
TL;DR: Three metabolites named phomopsin A, B and C, together with two known compounds cytosporone B (4) and C (5), were isolated from the mangrove endophytic fungus, Phomopsis sp.
Journal ArticleDOI
Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces.
Weishan Wang,Weishan Wang,Shanshan Li,Zilong Li,Jie Zhang,Keqiang Fan,Gao-Yi Tan,Guomin Ai,Sin Man Lam,Guanghou Shui,Zhiheng Yang,Hongzhong Lu,Pinjiao Jin,Yihong Li,Xiangyin Chen,Xuekui Xia,Xueting Liu,H. Kathleen Dannelly,Chen Yang,Yi Yang,Siliang Zhang,Gil Alterovitz,Wensheng Xiang,Lixin Zhang +23 more
TL;DR: This work devised a strategy named ‘dynamic degradation of TAG’ (ddTAG) to mobilize the TAG pool and increase polyketide biosynthesis and increased the titer of avermectin B1a in a 180-m3 industrial-scale fermentation, which is the highest titer ever reported.
Journal ArticleDOI
Secalonic acid D induced leukemia cell apoptosis and cell cycle arrest of G1 with involvement of GSK-3β/β-catenin/c-Myc pathway
Jian Ye Zhang,Li Yang Tao,Yong Ju Liang,Yan Yan Yan,Chun Ling Dai,Xuekui Xia,Zhigang She,Yong Cheng Lin,Li Wu Fu +8 more
TL;DR: The data indicated that downregulation of c-Myc and cell cycle arrest of G1 phase were caused not by formation of G-quadruplex structures but by activation of GSK-3β followed by degradation of β-catenin.