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Xuezhi Qiao

Bio: Xuezhi Qiao is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Materials science & Medicine. The author has an hindex of 13, co-authored 16 publications receiving 568 citations.

Papers
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Journal ArticleDOI
TL;DR: Gaseous aldehydes that are released as a result of tumor-specific tissue composition and metabolism, thereby acting as indicators of lung cancer, are guided onto SERS-active GSPs substrates through a ZIF-8 channel, demonstrating tremendous prospects for in vitro diagnoses of early stage lung cancer.
Abstract: Surface enhanced Raman scattering (SERS) is a trace detection technique that extends even to single molecule detection. Its potential application to the noninvasive recognition of lung malignancies by detecting volatile organic compounds (VOCs) that serve as biomarkers would be a breakthrough in early cancer diagnostics. This application, however, is currently limited by two main factors: (1) most VOC biomarkers exhibit only weak Raman scattering; and (2) the high mobility of gaseous molecules results in a low adsorptivity on solid substrates. To enhance the adsorption of gaseous molecules, a ZIF-8 layer is coated onto a self-assembly of gold superparticles (GSPs) in order to slow the flow rate of gaseous biomarkers and depress the exponential decay of the electromagnetic field around the GSP surfaces. Gaseous aldehydes that are released as a result of tumor-specific tissue composition and metabolism, thereby acting as indicators of lung cancer, are guided onto SERS-active GSPs substrates through a ZIF-8 channel. Through a Schiff base reaction with 4-aminothiophenol pregrafted onto gold GSPs, gaseous aldehydes are captured with a 10 ppb limit of detection, demonstrating tremendous prospects for in vitro diagnoses of early stage lung cancer.

267 citations

Journal ArticleDOI
Zhen Zhang1, Wei Yu1, Jing Wang1, Dan Luo1, Xuezhi Qiao1, Xiaoyun Qin1, Tie Wang1 
TL;DR: The sensitivity of this operational SERS strategy to detection of lung cancer biomarkers was not affected by the humidity, which represented a great potential in fast, easy, cost-effective, and noninvasive recognition of lung malignancies.
Abstract: Surface-enhanced Raman scattering (SERS) is expected as a technique that even theoretically detected chemicals at the single molecule level by surface plasmon phenomena of noble metal nanostructures. Insensitivity of detecting Raman weak-intensity molecules and low adsorptivity of gaseous molecules on solid substrates are two main factors hindering the application of SERS in gas detectors. In this manuscript, we demonstrated an operational SERS strategy to detect gaseous Raman weak-intensity aldehydes that have been considered as a biomarker of lung cancer for abnormal content was measured in volatile organic compounds (VOCs) of lung cancer patients. To enhance the adsorption of gaseous molecules, dendritic Ag nanocrystals mimicking the structural feature (dendritic) of moth’s antennae were formed, wherein the existence of numerous cavity traps in Ag dendritic nanocrystals prolonged reaction time of the gaseous molecules on the surface of solid surface through the “cavity-vortex” effect. By the nucleophil...

76 citations

Journal ArticleDOI
TL;DR: A stacked-nanosheet MOF based catalyst with precisely controlled coordination sites on the surface and enhanced catalytic reactivity and structural robustness is prepared and could form a basis for the rational design and construction of highly efficient and robust catalysts in the field of single-atom or ion catalysis.
Abstract: Optimising the supported modes of atom or ion dispersal onto substrates, to synchronously integrate high reactivity and robust stability in catalytic conversion, is an important yet challenging area of research. Here, theoretical calculations first show that three-coordinated copper (Cu) sites have higher activity than four-, two- and one-coordinated sites. A site-selective etching method is then introduced to prepare a stacked-nanosheet metal-organic framework (MOF, CASFZU-1)-based catalyst with precisely controlled coordination number sites on its surface. The turnover frequency value of CASFZU-1 with three-coordinated Cu sites, for cycloaddition reaction of CO2 with epoxides, greatly exceed those of other catalysts reported to date. Five successive catalytic cycles reveal the superior stability of CASFZU-1 in the stacked-nanosheet structure. This study could form a basis for the rational design and construction of highly efficient and robust catalysts in the field of single-atom or ion catalysis.

74 citations

Journal ArticleDOI
TL;DR: In this article, the authors design heterogeneous catalysts so that they can simultaneously integrate the efficiency and durability under reaction environments with respect to gas fuel production, such as hydrogen (H2).
Abstract: Redesigning heterogeneous catalysts so that they can simultaneously integrate the efficiency and durability under reaction environments with respect to gas fuel production, such as hydrogen (H2), o...

73 citations

Journal ArticleDOI
12 Sep 2019-Chem
TL;DR: An orthogonal approach to guide movable hemin-loaded mesoporous silica nanoparticles for the removal of intracellular ROS and the ability of these movable hollow nanoparticles to scavenge ROS based on the universal nature of this strategy was verified both in vitro and in vivo.

65 citations


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TL;DR: In this paper, the authors provide an updated survey of the field of halide perovskite nanocomposite colloidal synthesis, with a main focus on their colloidal synthetic routes to control shape, size and optical properties of the resulting nano-crystals.
Abstract: Metal halide perovskites represent a flourishing area of research, driven by both their potential application in photo-voltaics and optoelectronics, and for the fundamental science underpinning their unique optoelectronic properties. The advent of colloidal methods for the synthesis of halide perovskite nanocrystals has brought to the attention inter-esting aspects of this new type of materials, above all their defect-tolerance. This review aims to provide an updated survey of this fast-moving field, with a main focus on their colloidal synthesis. We examine the chemistry and the ca-pability of different colloidal synthetic routes to control the shape, size and optical properties of the resulting nano-crystals. We also provide an up to date overview of their post-synthesis transformations, and summarize the various so-lution processes aimed at fabricating halide perovskite-based nanocomposites. We then review the fundamental optical properties of halide perovskite nanocrystals, by focusing on their linear optical properties, on the effects of quantum confinement and, then, on the current knowledge of their exciton binding energies. We also discuss the emergence of non-linear phenomena such as multiphoton absorption, biexcitons and carrier multiplication. At last, we provide an outlook in the field, with the most cogent open questions and possible future directions.

836 citations

Journal ArticleDOI
TL;DR: This review aims to provide an up-to-date survey of this fast-moving field and will mainly focus on the different colloidal synthesis approaches that have been developed and on the fundamental optical properties of halide perovskite nanocrystals.
Abstract: Metal halide perovskites represent a flourishing area of research, which is driven by both their potential application in photovoltaics and optoelectronics and by the fundamental science behind their unique optoelectronic properties. The emergence of new colloidal methods for the synthesis of halide perovskite nanocrystals, as well as the interesting characteristics of this new type of material, has attracted the attention of many researchers. This review aims to provide an up-to-date survey of this fast-moving field and will mainly focus on the different colloidal synthesis approaches that have been developed. We will examine the chemistry and the capability of different colloidal synthetic routes with regard to controlling the shape, size, and optical properties of the resulting nanocrystals. We will also provide an up-to-date overview of their postsynthesis transformations, and summarize the various solution processes that are aimed at fabricating halide perovskite-based nanocomposites. Furthermore, we...

832 citations

Journal ArticleDOI
TL;DR: This review focuses on the design and fabrication of one-, two- and three-dimensional MOFs at micro/nanoscale, and their direct applications in batteries, supercapacitors and electrocatalysis.
Abstract: As a new class of crystalline porous materials, metal-organic frameworks (MOFs) have received great attention owing to their unique advantages of ultrahigh surface area, large pore volume and versatile applications. Developing different strategies to control the morphology and size of MOFs is very important for their practical applications. Recently, micro/nanosized MOFs have been regarded as promising candidates for electrode materials with excellent performances, which not only bridge the gap between fundamental MOF science and forward-looking applications, but also provide an opportunity to make clear the relationship between morphologies and properties. This review focuses on the design and fabrication of one-, two- and three-dimensional MOFs at micro/nanoscale, and their direct applications in batteries, supercapacitors and electrocatalysis. A discussion on challenges and future prospects of the synthesis and electrochemical applications of micro/nanoscaled MOF materials is presented.

615 citations

Journal ArticleDOI
TL;DR: In this article, a synergistic method that combines the Cu-Zn solid solution interface on a copper mesh skeleton with good zinc affinity and a polyacrylamide electrolyte additive to modify the zinc anode, which can greatly reduce the overpotential of the zinc nucleation and increase the stability of zinc deposition, is presented.
Abstract: Rechargeable aqueous zinc-ion batteries have been considered as a promising candidate for next-generation batteries. However, the formation of zinc dendrites are the most severe problems limiting their practical applications. To develop stable zinc metal anodes, a synergistic method is presented that combines the Cu-Zn solid solution interface on a copper mesh skeleton with good zinc affinity and a polyacrylamide electrolyte additive to modify the zinc anode, which can greatly reduce the overpotential of the zinc nucleation and increase the stability of zinc deposition. The as-prepared zinc anodes show a dendrite-free plating/stripping behavior over a wide range of current densities. The symmetric cell using this dendrite-free anode can be cycled for more than 280 h with a very low voltage hysteresis (93.1 mV) at a discharge depth of 80 %. The high capacity retention and low polarization are also realized in Zn/MnO2 full cells.

509 citations

Journal ArticleDOI
TL;DR: A compositional encyclopedia of SACs is provided, celebrating the 10th anniversary of the introduction of this term, and examines the coordination structures and associated properties accessed through distinct single-atom-host combinations and relate them to their main applications in thermo-, electro-, and photocatalysis.
Abstract: Isolated atoms featuring unique reactivity are at the heart of enzymatic and homogeneous catalysts. In contrast, although the concept has long existed, single-atom heterogeneous catalysts (SACs) have only recently gained prominence. Host materials have similar functions to ligands in homogeneous catalysts, determining the stability, local environment, and electronic properties of isolated atoms and thus providing a platform for tailoring heterogeneous catalysts for targeted applications. Within just a decade, we have witnessed many examples of SACs both disrupting diverse fields of heterogeneous catalysis with their distinctive reactivity and substantially enriching our understanding of molecular processes on surfaces. To date, the term SAC mostly refers to late transition metal-based systems, but numerous examples exist in which isolated atoms of other elements play key catalytic roles. This review provides a compositional encyclopedia of SACs, celebrating the 10th anniversary of the introduction of this term. By defining single-atom catalysis in the broadest sense, we explore the full elemental diversity, joining different areas across the whole periodic table, and discussing historical milestones and recent developments. In particular, we examine the coordination structures and associated properties accessed through distinct single-atom-host combinations and relate them to their main applications in thermo-, electro-, and photocatalysis, revealing trends in element-specific evolution, host design, and uses. Finally, we highlight frontiers in the field, including multimetallic SACs, atom proximity control, and possible applications for multistep and cascade reactions, identifying challenges, and propose directions for future development in this flourishing field.

505 citations