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Y. N. Seetharam

Bio: Y. N. Seetharam is an academic researcher. The author has contributed to research in topics: Strychnos potatorum & Brucine. The author has an hindex of 1, co-authored 1 publications receiving 2 citations.

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01 Jan 2012
TL;DR: A B ST R A C T Strychnos potatorum (Clearing nut) is an important medicinal plant used in the traditional and folk medicine for treating several aliments including microbial infections, diarrhoea and diabetes.
Abstract: A B ST R A C T Strychnos potatorum (Clearing nut), an important medicinal plant used in the traditional and folk medicine for treating several aliments including microbial infections, diarrhoea and diabetes. Some of its pharmacognostic studies such as fluorescent, organoleptic, ash and mineral contents of root, stem bark and seed (both collected and market) , and GC- alkaloid profiles of seed have been investigated. Considerable colour variations in the fluorescent behaviour of raw drugs were observed. The highest yields were obtained for the aqueous extracts followed by ethanol, petroleum ether and chloroform extracts. The colour of the extracts thus obtained have from ivory to dark brown and bitter to pungent bitter in taste. Higher values of the total ash and insoluble acid contents were recorded for the stem bark, followed by root and seed samples. Considerable amounts of iron and copper found in all parts of the plant. However, lead, a toxic element was found in trace amount in the market seed sample. Further, the GC-alkaloid profiles of seed samples have shown significant variation in terms of percent area of peaks. Furthermore, the co-TLC study has revealed the absence of strychnine and brucine from the seed sample.

2 citations


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Journal Article
TL;DR: A preliminary phytochemical screening of seed and leaf of Strychnos wallichiana, an Asiatic woody liana species belongs to the family Loganiaceae, revealed the presence of alkaloids, phenols, glycosides, flavonoids, saponins and sterols.
Abstract: A preliminary phytochemical screening of seed and leaf of Strychnos wallichiana , an Asiatic woody liana species belongs to the family Loganiaceae revealed the presence of alkaloids, phenols, glycosides, flavonoids, saponins and sterols. Further, the HPLC chromatogram of alkaloid profile of seed has shown twelve prominent alkaloid peaks. Furthermore, the methanol and aqueous extracts were evaluated for in vitro antimicrobial properties against the selected bacteria and fungi at the concentration 2 mg/ml and 4 mg/ml, respectively using agar well diffusion assay. The findings have revealed considerable to significant inhibition activity of pathogens tested.

2 citations

01 Jan 2013
TL;DR: In this paper, a preliminary phytochemical evaluation revealed the presence of glycosides, saponins, phytosterols, phenolic compounds, flavanoids, tannins, carbohydrates and triterpenoids.
Abstract: Medicinal plants contain some organic compounds which provide definite physiological action on the human body. The present study was aimed at physico chemical and preliminary phytochemical screening of Lactuca scariola Linn, Basella alba Linn and Celosia Argentea Linn leaf extracts. The dried leaves powder was subjected to successive Soxhlet extraction using Petroleum ether, methanol and water. These solvent extracts were subjected to a preliminary phytochemical screening to detect the different chemical principles present viz., carbohydrates, proteins, amino acids, steroids, glycosides, alkaloids, flavonoids, tannins and phenolic compounds, fixed oils. The phytochemical evaluation revealed the presence of glycosides, saponins, phytosterols, phenolic compounds, flavanoids, tannins, carbohydrates and triterpenoids.The diversity of phytochemicals found suggests that that aqueous and methanolic solvent extracts of these tested plants contain medicinally important bioactive compounds and it justifies their use in the traditional medicines for the treatment of different diseases.

1 citations