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Y. V. Kravatsky
Researcher at Engelhardt Institute of Molecular Biology
Publications - 11
Citations - 87
Y. V. Kravatsky is an academic researcher from Engelhardt Institute of Molecular Biology. The author has contributed to research in topics: Gene & Gene silencing. The author has an hindex of 5, co-authored 11 publications receiving 80 citations.
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Journal ArticleDOI
Coexistence of different base periodicities in prokaryotic genomes as related to DNA curvature, supercoiling, and transcription.
TL;DR: The comparison with available experimental data indicates that promoters with the most pronounced periodicities may be related to the supercoiling-sensitive genes.
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Structural attributes of nucleotide sequences in promoter regions of supercoiling-sensitive genes: how to relate microarray expression data with genomic sequences.
TL;DR: F Fourier analysis of promoter sequences for supercoiling-sensitive genes reveals the tendency in selection of sequences with helical periodicities close to 10nt for relaxation-induced genes and to 11nt for Relaxation-repressed genes.
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Mapping of genomic double-strand breaks by ligation of biotinylated oligonucleotides to forum domains: Analysis of the data obtained for human rDNA units
Nickolai A. Tchurikov,Olga V. Kretova,D. M. Fedoseeva,V. R. Chechetkin,Maria A. Gorbacheva,A.A. Karnaukhov,G.I. Kravatskaya,Y. V. Kravatsky +7 more
TL;DR: The experimental design and bioinformatics analysis of the data deposited in the Gene Expression Omnibus with accession number GSE49302 and associated with the study published in the Journal of Molecular Cell Biology are described.
Journal ArticleDOI
Genome-wide mapping of hot spots of DNA double-strand breaks in human cells as a tool for epigenetic studies and cancer genomics
Nickolai A. Tchurikov,Olga V. Kretova,D. M. Fedoseeva,V. R. Chechetkin,Maria A. Gorbacheva,A V Snezhkina,Ildar R. Alembekov,G.I. Kravatskaya,Y. V. Kravatsky +8 more
TL;DR: Using Illumina sequencing to map DSBs in chromosomes of human HEK293T cells and describing in detail the experimental design and bioinformatics analysis of the data deposited in the Gene Expression Omnibus are associated with the study published in DNA Research.
Journal ArticleDOI
[Homeotic DUX4 Genes that Control Human Embryonic Development at the Two-Cell Stage Are Surrounded by Regions Contacting with rDNA Gene Clusters].
Olga V. Kretova,D. M. Fedoseeva,Y. V. Kravatsky,Ildar R. Alembekov,I Y Slovohotov,Nickolai A. Tchurikov +5 more
TL;DR: It is found that the DUX4 genes located in the subtelomeric region of human chromosome 4 are surrounded by regions that are often in contact with the rRNAs, and it is assumed that the rRNA gene contacts are important in silencing these Dux4 gene copies.