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Yan He
Researcher at Ocean University of China
Publications - 57
Citations - 2840
Yan He is an academic researcher from Ocean University of China. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 17, co-authored 47 publications receiving 2281 citations. Previous affiliations of Yan He include Rutgers University.
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Journal ArticleDOI
The oyster genome reveals stress adaptation and complexity of shell formation
Guofan Zhang,Xiaodong Fang,Ximing Guo,Li Li,Ruibang Luo,Fei Xu,Pengcheng Yang,Linlin Zhang,Xiaotong Wang,Haigang Qi,Zhiqiang Xiong,Huayong Que,Yinlong Xie,Peter W. H. Holland,Jordi Paps,Yabing Zhu,Fucun Wu,Yuanxin Chen,Jiafeng Wang,Chunfang Peng,Jie Meng,Lan Yang,Jun Liu,Bo Wen,Na Zhang,Zhiyong Huang,Qihui Zhu,Yue Feng,Andrew S. Mount,Dennis Hedgecock,Zhe Xu,Yunjie Liu,Tomislav Domazet-Lošo,Yishuai Du,Xiaoqing Sun,Shoudu Zhang,Binghang Liu,Peizhou Cheng,Xuanting Jiang,Juan Li,Dingding Fan,Wei Wang,Wenjing Fu,Tong Wang,Bo Wang,Jibiao Zhang,Zhiyu Peng,Yingxiang Li,Na Li,Jinpeng Wang,Maoshan Chen,Yan He,Fengji Tan,Xiaorui Song,Qiumei Zheng,Ronglian Huang,Hailong Yang,Du Xuedi,Li Chen,Mei Yang,Patrick M. Gaffney,Shan Wang,Longhai Luo,Zhicai She,Yao Ming,Huang Wen,Shu Zhang,Baoyu Huang,Yong Zhang,Tao Qu,Peixiang Ni,Guoying Miao,Junyi Wang,Qiang Wang,Christian E. W. Steinberg,Haiyan Wang,Ning Li,Lumin Qian,Guojie Zhang,Yingrui Li,Huanming Yang,Xiao Liu,Jian Wang,Ye Yin,Jun Wang +84 more
TL;DR: The sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy and transcriptomes of development and stress response and the proteome of the shell are reported, showing that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes.
Journal ArticleDOI
Immune and stress responses in oysters with insights on adaptation.
TL;DR: The great diversity in immune and stress response genes exhibited by expanded gene families as well as high sequence and structural polymorphisms may be central to oyster's adaptation to highly stressful and widely changing environments.
Journal ArticleDOI
Transcriptome analysis reveals strong and complex antiviral response in a mollusc
Yan He,Aude Jouaux,Susan E. Ford,Christophe Lelong,Pascal Sourdaine,Michel Mathieu,Ximing Guo +6 more
TL;DR: The mobilization and complex regulation of expanded innate immune-gene families highlights the oyster genome's adaptation to a virus-rich marine environment and provides unprecedented insights into antiviral response in a mollusc.
Journal ArticleDOI
Polymorphism in a serine protease inhibitor gene and its association with disease resistance in the eastern oyster (Crassostrea virginica Gmelin).
TL;DR: In this paper, the authors identified polymorphism in the cvSI-1 gene and studied its association with improved survival after disease-caused mortalities and in disease-resistant eastern oyster strains.
Journal ArticleDOI
Transcriptome sequencing of Zhikong scallop (Chlamys farreri) and comparative transcriptomic analysis with Yesso scallop (Patinopecten yessoensis).
Shan Wang,Rui Hou,Zhenmin Bao,Huixia Du,Yan He,Hailin Su,Yueyue Zhang,Xiaoteng Fu,Wenqian Jiao,Yan Li,Lingling Zhang,Shi Wang,Xiaoli Hu +12 more
TL;DR: De novo transcriptome sequencing is performed to produce the most comprehensive expressed sequence tag resource for Zhikong scallop (Chlamys farreri), and the first large-scale transcriptome comparison for scallops is performed, which identified a number of putative fast-evolving genes, which may play an important role in scAllop speciation and/or local adaptation.