https://pubs.rsc.org/en/content/articlepdf/2019/NP/C8NP00092A

Marine natural products.

Chem. Pharm. Bull.(オピニオン)

Diterpenoids from Isodon species and their biological activities

S-Adenosylmethionine Jose M. Mato and Shelly C. Lu Aloe Vera Santiago Rodriguez, Steven Dentali, and Devon Powell Androstenedione Benjamin Z. Leder L-Arginine Mauro Maccario, Guglielmo Beccuti, Valentina Gasco, Mariangela Seardo, Gianluca Aimaretti, Emanuela Arvat, Fabio Lanfranco, and Ezio Ghigo Astragalus Roy Upton Bilberry Marilyn Barrett Biotin Donald M. Mock Bitter Orange Steffany Haaz, K. Y. Williams, Kevin R. Fontaine, and David B. Allison Black Cohosh Daniel S. Fabricant, Elizabeth C. Krause, and Norman R. Farnsworth Blue-Green Algae (Cyanobacteria) WayneW. Carmichael and Mary Stukenberg with Joseph M. Betz Boron Curtiss Hunt Caffeine Harris R. Lieberman, Christina E. Carvey, and Lauren A. Thompson Calcium Robert P. Heaney Propionyl-L-Carnitine Charles J. Rebouche ss-Carotene Elizabeth J. Johnson and Robert M. Russell Carotenoids Overview Elizabeth J. Johnson and Robert M. Russell Cascara Sagrada Kapil K. Soni and Gail B. Mahady Chaste Tree Gail B. Mahady, Joanna L. Michel, and Kapil K. Soni Choline Steven H. Zeisel Chondroitin Sulfate Karla L. Miller and Daniel O. Clegg Chromium Richard A. Anderson andWilliam T. Cefalu Coenzyme Q10 Gustav Dallner and Roland Stocker Conjugated Linoleic Acid Kristina B. Martinez, Arion J. Kennedy, and Michael K. McIntosh Copper Leslie M. Klevay Cordyceps John Holliday, Matt Cleaver, Mojca Tajnik, Joseph M. Cerecedes, and Solomon P. Wasser Cranberry Marguerite A. Klein Creatine G. S. Salomons, C. Jakobs, and M. Wyss Dong Quai Roy Upton Dehydroepiandrosterone Salvatore Alesci, Irini Manoli, and Marc R. Blackman Rudolf Bauer and Karin Woelkart Elderberry Madeleine Mumcuoglu, Daniel Safirman, and Mina Ferne Eleuthero Josef A. Brinckmann Ephedra Anne L. Thurn with Joseph M. Betz Evening Primrose Fereidoon Shahidi and Homan Miraliakbari Feverfew Dennis V. C. Awang Flaxseed Lilian U. Thompson and Julie K. Mason Folate Pamela Bagley and Barry Shane French Maritime Pine Peter J. Rohdewald Garcinia Frank Greenway Garlic J. A. Milner Ginger Tieraona Low Dog Ginkgo Kristian Stromgaard, Stine B. Vogensen, Joseph Steet, and Koji Nakanishi Ginseng, American Chong-Zhi Wang and Chun-Su Yuan Ginseng, Asian Lee Jia and Fabio Soldati Glucosamine Karla L. Miller and Daniel O. Clegg Glutamine Steven F. Abcouwer Goldenseal Dennis J. McKenna and Gregory A. Plotnikoff Grape Seed Extract Dallas L. Clouatre, Chithan Kandaswami, and Kevin M. Connolly Green Tea Polyphenols Shengmin Sang, Joshua D. Lambert, Chi-Tang Ho, and Chung S. Yang Hawthorn Egon Koch, Werner R. Busse,Wiltrud Juretzek, and Vitali Chevts 5-Hydroxytryptophan Pedro Del Corral, Kathryn S. King, and Karel Pacak Iron Laura E. Murray-Kolb and John Beard Isoflavones Mark Messina Isothiocyanates Elizabeth H. Jeffery and Anna-Sigrid Keck Kava Michael J. Balick, Katherine Herrera, and Steven M. Musser Lactobacilli and Bifidobacteria Linda C. Duffy, Stephen Sporn, Patricia Hibberd, Carol Pontzer, Gloria Solano-Aguilar, Susan V. Lynch, and Crystal McDade-Ngutter Licorice Decio Armanini, Cristina Fiore, Jens Bielenberg, and Eugenio Ragazzi alpha-Lipoic Acid/Thioctic Acid Donald B. McCormick Lutein John Paul SanGiovanni, Emily Y. Chew, and Elizabeth J. Johnson Lycopene Rachel Kopec, Steven J. Schwartz, and Craig Hadley Maca Ilias Muhammad, Jianping Zhao, and Ikhlas A. Khan Magnesium Robert K. Rude Melatonin Amnon Brzezinski and Richard J. Wurtman Milk Thistle Elena Ladas, David J. Kroll, and Kara M. Kelly Niacin Christelle Bourgeois and Joel Moss Noni Alison D. Pawlus, Bao-Ning Su, Ye Deng, and A. Douglas Kinghorn Omega-3 Fatty Acids William S. Harris Omega-6 Fatty Acids William L. Smith and Bill Lands Pancreatic Enzymes Naresh Sundaresan, Unwanaobong Nseyo, and Joel Moss Pantothenic Acid Lawrence Sweetman Pau d'Arco Memory P. F. Elvin-Lewis and Walter H. Lewis Phosphorus John J. B. Anderson and Sanford C. Garner Polyphenols Overview Navindra P. Seeram Proanthocyanidins Catherine Kwik-Uribe, Rebecca Robbins, and Gary Beecher Pygeum Franc,ois G. Brackman and Alan Edgar with Paul M. Coates Quercetin Jae B. Park Red Clover Elizabeth C. Krause, Nancy L. Booth, Colleen E. Piersen, and Norman R. Farnsworth Reishi Solomon P. Wasser Riboflavin Richard S. Rivlin Saw Palmetto Edward M. Croom and Michael Chan Selenium Roger A. Sunde Shiitake Solomon P. Wasser St. John's Wort Jerry M. Cott Taurine Robin J. Marles, Valerie A. Assinewe, Julia A. Fogg, Milosz Kaczmarek, and Michael C. W. Sek Thiamin Hamid M. Said Turmeric Janet L. Funk Valerian Dennis V. C. Awang Vitamin A A. Catharine Ross Vitamin B6 James E. Leklem Vitamin B12 Lindsay H. Allen Vitamin C Sebastian Padayatty, Michael Graham Espey, and Mark Levine Vitamin D Patsy Brannon, Mary Frances Picciano, and Michelle K. McGuire Vitamin E Maret G. Traber Vitamin K J. W. Suttie Yohimbe Joseph M. Betz Zinc Carolyn S. Chung and Janet C. King Index

Encyclopedia of dietary supplements.

Therapeutic orchids: traditional uses and recent advances--an overview.

One hundred and thirty endophytic fungi isolated from 12 Chinese traditional medicinal plants collected at Yuanmou county and Dawei Mountain, Yunnan province, southwest China, were tested for antitumour and antifungal activities by MTT assay on human gastric tumour cell line BGC-823 and the growth inhibition test against 7 phytopathogenic fungi. The results showed that fermentation broths from 9.2% of the isolates exhibited antitumour activity and 30% exhibited antifungal activity, moreover, some of them exhibited broad-spectrum antifungal activity. The active isolates were identified to 32 taxa. The results indicate that the endophytic fungi of Chinese traditional medicinal plants are promising sources of novel bioactive compounds.

Screening for endophytic fungi with antitumour and antifungal activities from Chinese medicinal plants

Cytotoxic phenolics from Bulbophyllum odoratissimum

Two new cycloartane-type triterpene glycosides, namely cimicifoetisides A (1) and B (2), along with seven known compounds cimigenol, 25-O-acetylcimigenol, cimigenol 3-O-β-D-xylopyranoside, 12β-hydroxycimigenol 3-O-β-D-xylopyranoside, cimigenol 3-O-α-L-arabinopyranoside, 25-deoxyshengmanol 3-O-β-D-xylopyranoside and cimilactone A, were isolated from the rhizomes of Cimicifuga foetida. Their structures were elucidated as cimigenol 3-O-(2'-O-acetyl)-α-L-arabinopyranoside (1) and 25-O-acetylcimigenol 3-O-(2'-O-acetyl)-α-L-arabinopyranoside (2). Both compounds 1 and 2 exhibited potent cytotoxicity against rat EAC (Ehrlich ascites carcinoma) and MDA-MB-A231 (human breast cancer) cells with IC50 values of 0.52 and 6.74 μM for 1, and 0.19 and 10.21 μM for 2, suggesting their potential for further investigation as anti-cancer agents.

https://www.beilstein-journals.org/bjoc/content/pdf/1860-5397-3-3.pdf

Cimicifoetisides A and B, two cytotoxic cycloartane triterpenoid glycosides from the rhizomes of Cimicifuga foetida, inhibit proliferation of cancer cells.

Seven new 9,19-cycloartane triterpene glycosides. 25-O-acetylcimigenol-3-O-[2'-O-(E)-2-butenoyl]-beta-D-xylopyranoside (1), 25-O-acetylcimigenol-3-O-[4'-O-(E)-2-butenoyl]-beta-D-xylopyranoside (2), 25-O-acetylcimigenol-3-O-[3'-O-acetyl]-beta-D-xylopyranoside (3), 25-O-acetylcimigenol-3-O-[4'-O-acetyl]-beta-D-xylopyranoside (4), 25-O-acetyl-12 beta-acetoxycimingenol-3-O-beta-D-xylopyranoside (5), 3'-O-acetylactein (6). and 3'-O-acetyl-23-epi-26-deoxyactein (7), together with eight known compounds (8-15), were isolated from the roots of Cimicifuga fetida. Their structures were established by spectroscopic and chemical methods. Most of these compounds Showed more selective and higher cytotoxicity against the human HepG2 cell line than against the MCF7, HT29. and MKN28 cell lines. compounds 2, 3, and 7 exhibited significant cytotoxicity against HepG2 cells, with IC(50) values of 1.29, 0.71, and 1.41 mu M, respectively.

https://pubs.acs.org/doi/pdf/10.1021/np1003559

Yanli Zhang

Papers

Screening for endophytic fungi with antitumour and antifungal activities from Chinese medicinal plants

Cytotoxic phenolics from Bulbophyllum odoratissimum

Cimicifoetisides A and B, two cytotoxic cycloartane triterpenoid glycosides from the rhizomes of Cimicifuga foetida, inhibit proliferation of cancer cells.

Cytotoxic Chemical Constituents from the Roots of Cimicifuga fetida

1,4,5-Trihydroxy-7-methoxy-9H-fluoren-9-one, a new cytotoxic compound from Dendrobium chrysotoxum