Y
Yanling Zhang
Researcher at Max Planck Society
Publications - 6
Citations - 1458
Yanling Zhang is an academic researcher from Max Planck Society. The author has contributed to research in topics: Proteomics & Proteome. The author has an hindex of 4, co-authored 4 publications receiving 1339 citations. Previous affiliations of Yanling Zhang include Beijing Institute of Genomics.
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Journal ArticleDOI
The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins.
Jun Adachi,Chanchal Kumar,Yanling Zhang,Yanling Zhang,Jesper V. Olsen,Jesper V. Olsen,Matthias Mann +6 more
TL;DR: The analysis provides a high-confidence set of proteins present in human urinary proteome and provides a useful reference for comparing datasets obtained using different methodologies and may prove useful in biomarker discovery in the future.
Journal ArticleDOI
A Mammalian Organelle Map by Protein Correlation Profiling
Leonard J. Foster,Carmen L. de Hoog,Carmen L. de Hoog,Yanling Zhang,Yanling Zhang,Yong Zhang,Yong Zhang,Xiaohui Xie,Vamsi K. Mootha,Vamsi K. Mootha,Matthias Mann,Matthias Mann +11 more
TL;DR: This analysis ties biochemistry, cell biology, and genomics into a common framework for organelle analysis and identifies networks of coexpressed genes, cis-regulatory motifs, and putative transcriptional regulators involved in organelle biogenesis.
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In-depth Analysis of the Adipocyte Proteome by Mass Spectrometry and Bioinformatics
TL;DR: The adipocyte proteome was investigated by combining high accuracy, high sensitivity protein identification technology with subcellular fractionation of nuclei, mitochondria, membrane, and cytosol of 3T3-L1 adipocytes to identify 3,287 proteins, making this one of the largest high confidence proteomes reported to date.
Journal ArticleDOI
MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes
Yanling Zhang,Yanling Zhang,Yong Zhang,Yong Zhang,Jun Adachi,Jesper V. Olsen,Rong Shi,Gustavo A. de Souza,Erica M. Pasini,Leonard J. Foster,Boris Macek,Alexandre Zougman,Chanchal Kumar,Jacek R. Wiśniewski,Wang Jun,Matthias Mann +15 more
TL;DR: The Max-Planck Unified (MAPU) proteome database contains several body fluid proteomes; including plasma, urine, and cerebrospinal fluid and can serve as reference proteomes in biomarker discovery.
Journal ArticleDOI
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Marah C. Runtsch,Stefano Angiari,Alexander Hooftman,Ridhima Wadhwa,Yanling Zhang,Yunan Zheng,Joseph S Spina,Melanie Ruzek,Maria A. Argiriadi,Anne F. McGettrick,Rui Santalla Mendez,Alessia Zotta,Christian G. Peace,Aoife Walsh,Roberta Chirillo,Emily Hams,Padraic G. Fallon,Ranjith Jayamaran,Kamal Dua,Alexandra C. Brown,Richard Kim,Jay C. Horvat,Philip M. Hansbro,Chu Wang,L. O'Neill +24 more
TL;DR: Itaconate and 4-octyl itaconate (OI) were shown to suppress the inflammatory response in pro-inflammatory "M1" macrophages and inhibit metabolic remodeling as mentioned in this paper .