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Yann Leverrier
Researcher at French Institute of Health and Medical Research
Publications - 17
Citations - 626
Yann Leverrier is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 11, co-authored 17 publications receiving 556 citations. Previous affiliations of Yann Leverrier include École normale supérieure de Lyon & University of Lyon.
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Journal ArticleDOI
Contrasting Cu, Fe, and Zn isotopic patterns in organs and body fluids of mice and sheep, with emphasis on cellular fractionation
Vincent Balter,Aline Lamboux,Antoine Zazzo,Philippe Telouk,Yann Leverrier,Jacqueline Marvel,Aidan P. Moloney,Frank J. Monahan,Olaf Schmidt,Francis Albarède +9 more
TL;DR: Differences in blood Zn isotope abundances between mice, sheep and humans may reflect a different prevalence of Zn ZIP transporters and the isotopically heavy Cu in the kidneys may reflect isotope fractionation during redox processes and may be relevant to ascorbate degradation into oxalate.
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Overexpression of Sp1 transcription factor induces apoptosis
Emmanuelle Deniaud,Joël Baguet,Joël Baguet,Anne-Laure Mathieu,Anne-Laure Mathieu,Gilles Pagès,Jacqueline Marvel,Jacqueline Marvel,Yann Leverrier,Yann Leverrier +9 more
TL;DR: It is shown that Sp1 levels in untransformed cells must be tightly regulated as Sp1 overexpression leads to the induction of apoptosis, and that cancer cells overexpressing Sp1 can avoid Sp1-induced apoptosis.
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Overexpression of Transcription Factor Sp1 Leads to Gene Expression Perturbations and Cell Cycle Inhibition
Emmanuelle Deniaud,Joël Baguet,Roxane Chalard,Roxane Chalard,Bariza Blanquier,Lilia Brinza,Julien Meunier,Julien Meunier,Marie-Cécile Michallet,Aurélie Laugraud,Claudette Ah-Soon,Anne Wierinckx,Marc Castellazzi,Joël Lachuer,Christian Gautier,Jacqueline Marvel,Yann Leverrier +16 more
TL;DR: It is shown that the binding to DNA of overexpressed Sp1 induces an inhibition of cell cycle progression that precedes apoptosis and a transcriptional response targeting genes containing Sp1 binding sites in their promoter or not suggesting both direct Sp1-driven transcription and indirect mechanisms.
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Development of antigen cross-presentation capacity in dendritic cells
Christiane Dresch,Yann Leverrier,Yann Leverrier,Jacqueline Marvel,Jacqueline Marvel,Ken Shortman,Ken Shortman,Ken Shortman +7 more
TL;DR: Increased cross-presentation capacity is thus induced in peripheral CD8 lineage DCs during inflammation or infection, because this capacity is already fully developed in steady-state thymic CD8(+) DCs, in accordance with their role in the deletion of self-reactive developing T cells.
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Synthesis of PEGylated gold nanostars and bipyramids for intracellular uptake.
Julien R. G. Navarro,Delphine Manchon,Frédéric Lerouge,Nicholas Blanchard,Sophie Marotte,Yann Leverrier,Jacqueline Marvel,Frédéric Chaput,Guillaume Micouin,Ana-Maria Gabudean,Alexis Mosset,E. Cottancin,Patrice L. Baldeck,Kenji Kamada,Kenji Kamada,Stephane Parola +15 more
TL;DR: In this paper, a complete study of P EGylated gold nanostars and PEGylated bipyramidal-like nanostructures is presented and it is shown that the biocompatible gold nanoparticles were easily internalized and most of them localized within the cells.