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Yann S. Mineur
Researcher at Yale University
Publications - 77
Citations - 6393
Yann S. Mineur is an academic researcher from Yale University. The author has contributed to research in topics: Nicotinic agonist & Nicotine. The author has an hindex of 35, co-authored 73 publications receiving 5313 citations. Previous affiliations of Yann S. Mineur include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior
TL;DR: Action of cholinergic signaling on cellular and synaptic properties of neurons in several brain areas are identified and consequences of this signaling on behaviors related to drug abuse, attention, food intake, and affect are discussed.
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It is not “either/or”: Activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood
TL;DR: It is concluded that there are effects of nAChR activation and desensitization on drug reinforcement and affective behavior, and that both processes are important in the behavioral consequences of nicotine in tobacco smoking.
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Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice.
TL;DR: The goals of these experiments are to obtain a clearer behavioral profile of genetically/phenotypically distant mouse strains after UCMS treatment and to evaluate the limitations and strengths of the UCMS model in mice.
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Nicotine Decreases Food Intake Through Activation of POMC Neurons
Yann S. Mineur,Alfonso Abizaid,Yan Rao,Ramiro Salas,Ralph J. DiLeone,Daniela Gündisch,Sabrina Diano,Mariella De Biasi,Tamas L. Horvath,Xiao-Bing Gao,Marina R. Picciotto +10 more
TL;DR: It is demonstrated that nicotine decreases food intake and body weight by influencing the hypothalamic melanocortin system and identifies critical molecular and synaptic mechanisms involved in nicotine-induced decreases in appetite.
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Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior.
Yann S. Mineur,Adetokunbo Obayemi,Mattis B. Wigestrand,Gianna M. Fote,Cali A. Calarco,Alice M. Li,Marina R. Picciotto +6 more
TL;DR: It is demonstrated that ACh signaling in the hippocampus promotes behaviors related to anxiety and depression, and abnormalities in the cholinergic system may be critical for the etiology of mood disorders and could represent an endophenotype of depression.