Yanyan Hu

TL;DR: The high prevalence of MCRPEC in the community poses a substantial risk for colistin usage in clinical practice and suggests the need for intestinal screening of mCR-1 carriers in intensive care units in Chinese hospitals, and suggests that aquaculture is a significant reservoir of mcr-1.

TL;DR: This study is the first to report the molecular homology analysis of CTX-M-producing E. coli isolates collected from water, swine, and healthy and hospitalized humans, suggesting that pathogens in the environment might originate both from humans and from animals.

TL;DR: The prevalence of Carbapenem-resistant Klebsiella pneumoniae (CRKP) increased from 2.5%, 2008 to 15.8%, 2018, and the main CRKP sequence type was ST11, and bla KPC-2 was the most prevalent gene variant.

TL;DR: This is the first report of rapid emergence of KPC-2-producing E. coli ST131 in China, and 13 isolates were consistent with the genetic environment in pE1, showing high-level carbapenem resistance.

TL;DR: The incidence ofCREC carriage in healthy people in China was small; however, the co-existence of CREC with mcr-1 is disconcerting, and pre-screening prior to admission and monitoring of patients on high-dependency wards is highly recommended to control and prevent the dissemination of CRE in hospitals.