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Yasukazu Ogino
Researcher at Massachusetts Institute of Technology
Publications - 10
Citations - 527
Yasukazu Ogino is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Dihydroxylation & Catalysis. The author has an hindex of 6, co-authored 10 publications receiving 520 citations.
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New ligands double the scope of the catalytic asymmetric dihydroxylation of olefins
K. Barry Sharpless,Willi Amberg,Matthias Beller,Hou Chen,Jens Hartung,Yasuhiro Kawanami,Doris Lubben,Eric Manoury,Yasukazu Ogino,Tomoyuki Shibata,Tatsuzo Ukita +10 more
TL;DR: Improved ligands render terminal olefins good substrates for the osmium-catalyzed asymmetric dihydroxylation (ADH) process as discussed by the authors.
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Preclusion of the “second cycle” in the osmium-catalyzed asymmetric dihydroxylation of olefins leads to a superior process
TL;DR: In this article, the highest enantioselectivities were achieved in catalytic asymmetric dihydroxylations using potassium hexacyanoferrate(III) [potassium ferricyanide, K3Fe(CN)6] as the reoxidant.
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Syntheses and crystal structures of the cinchona alkaloid derivatives used as ligands in the osmium-catalyzed asymmetric dihydroxylation of olefins
Willi Amberg,Youssef L. Bennani,Raj K. Chadha,Gerard A. Crispino,William D. Davis,Jens Hartung,Kyu Sung Jeong,Yasukazu Ogino,Tomoyuki Shibata,K. Barry Sharpless +9 more
TL;DR: Experimental procedures for the preparation of two classes of derivatives of the cinchona alkaloids dihydroquinine and dihydronidine are described in this paper, where they serve as highly enantioselective ligands for the osmium tetraoxide catalyzed asymmetric dihydroxylation (AD) of olefins.
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On the timing of hydrolysis / reoxidation in the osmium-catalyzed asymmetric dihydroxylation of olefins using potassium ferricyanide as the reoxidant
TL;DR: In this paper, it was shown that the asymmetric dihydroxylation of olefins using potassium ferricyanide as the stoichiometric reoxidant is a non-enantioselective cycle.
Journal ArticleDOI
A ligand structure-enantioselectivity relationship for the osmium-catalyzed asymmetric dihydroxylation of olefins
Yasukazu Ogino,Hou Chen,Eric Manoury,Tomoyuki Shibata,Matthias Beller,Doris Lubben,K. Barry Sharpless +6 more
TL;DR: In this paper, the highest enantioselectivities for various olefins were obtained in the osmium-catalyzed asymmetric dihydroxylation using new 9-O-aromatic dihydroquinidine and dihydronine ligands.