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Yi Chen

Researcher at Chinese Academy of Sciences

Publications -  5695
Citations -  344243

Yi Chen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Large Hadron Collider & Medicine. The author has an hindex of 217, co-authored 4342 publications receiving 293080 citations. Previous affiliations of Yi Chen include Rochester Institute of Technology & National Institutes of Health.

Papers
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The genetic architecture of type 2 diabetes

Christian Fuchsberger, +349 more
- 11 Jul 2016 - 
TL;DR: In this paper, the authors performed whole-genome sequencing in 2,657 European individuals with and without diabetes, and exome sequencing for 12,940 individuals from five ancestry groups.
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Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning.

TL;DR: Using a supervised machine-learning algorithm, a molecular signature is generated that can classify metastatic HCC patients and identified genes that were relevant to metastasis and patient survival and osteopontin was identified as a lead gene in the signature.
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MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells.

TL;DR: It is shown that microRNA (miRNA)-34a (1p36.23) is generally expressed at lower levels in unfavorable primary NB tumors and cell lines relative to normal adrenal tissue and that reintroduction of this miRNA into three different NB cell lines causes a dramatic reduction in cell proliferation through the induction of a caspase-dependent apoptotic pathway.
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A gravitational wave observatory operating beyond the quantum shot-noise limit

J. Abadie, +614 more
- 11 Sep 2011 - 
TL;DR: In this paper, the authors demonstrate the squeezed-light enhancement of GEO600, which will be the GW observatory operated by the LIGO Scientific Collaboration in its search for GWs for the next 3-4 years.
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First M87 Event Horizon Telescope Results. V. Physical Origin of the Asymmetric Ring

Kazunori Akiyama, +262 more
TL;DR: In this article, a large library of models based on general relativistic magnetohydrodynamic (GRMHD) simulations and synthetic images produced by GRS was constructed and compared with the observed visibilities.