Yih-Ru Wu

TL;DR: Data collected demonstrate that there is a strong association between GBA mutations and Parkinson's disease, and those with a GBA mutation presented earlier with the disease, were more likely to have affected relatives, and were morelikely to have atypical clinical manifestations.

TL;DR: A 69‐year‐old woman with Parkinson's disease and levodopa‐induced dyskinesias had a deep brain stimulation electrode inserted into the right globus pallidus internus and postoperatively stimulation through macroelectrode contacts located in the posterior ventral pallidum controlled the patient's dysKinesias.

TL;DR: Results indicate means to suppress oxidative damage or to restore mitochondrial functions may be beneficial to HD patients and plasma MDA may be used as a potential biomarker to test treatment efficacy in the future, if confirmed in a larger, longitudinal study.

TL;DR: In this article, the authors show evidence for leucine-rich repeat kinase 2 (LRRK2) c.4883G>C (R1628P) as a risk factor in ethnic Chinese populations.

TL;DR: This study identified 2 apparently novel gene loci and found 9 previously identified European loci to be associated with PD in this large, meta-genome-wide association study in a worldwide population of Asian individuals and reports similarities and differences in genetic risk factors between Asian and European individuals in the risk for PD.