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Yijin Wang
Researcher at Chinese PLA General Hospital
Publications - 58
Citations - 9078
Yijin Wang is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: Hepatitis E virus & Hepatitis E. The author has an hindex of 21, co-authored 56 publications receiving 6759 citations. Previous affiliations of Yijin Wang include Southern University of Science and Technology & Erasmus University Rotterdam.
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Journal ArticleDOI
Pathological findings of COVID-19 associated with acute respiratory distress syndrome.
Zhe Xu,Lei Shi,Yijin Wang,Ji-Yuan Zhang,Lei Huang,Chao Zhang,Shuhong Liu,Peng Zhao,Hongxia Liu,Li Zhu,Yanhong Tai,Changqing Bai,Tingting Gao,Jin-Wen Song,Peng Xia,Jing-Hui Dong,Jingmin Zhao,Fu-Sheng Wang +17 more
TL;DR: O surto do novo coronavÃrus (COVID-19) em Wuhan, China, iniciado em dezembro de 2019, evoluiu para se tornar uma pandemia global A.
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SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19.
Yijin Wang,Shuhong Liu,Hongyang Liu,Li Wei,Fang Lin,Lina Jiang,Xi Li,Pengfei Xu,Lixin Zhang,Lihua Zhao,Cao Yun,Jiarui Kang,Jianfa Yang,Ling Li,Xiaoyan Liu,Yan Li,Ruifang Nie,Jinsong Mu,Fengmin Lu,Shousong Zhao,Jiangyang Lu,Jingmin Zhao +21 more
TL;DR: The liver enzyme abnormality was associated with disease severity, as well as a series of laboratory tests including higher A-aDO2, higher GGT, lower albumin, decreased CD4+ T cells and B lymphocytes, and histologically, massive hepatic apoptosis and a certain binuclear hepatocytes were observed.
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Clinical and pathological investigation of patients with severe COVID-19.
Shaohua Li,Lina Jiang,Xi Li,Fang Lin,Yijin Wang,Boan Li,Tianjun Jiang,Weimin An,Shuhong Liu,Hongyang Liu,Pengfei Xu,Lihua Zhao,Lixin Zhang,Jinsong Mu,Hongwei Wang,Jiarui Kang,Yan Li,Lei Huang,Caizhong Zhu,Shousong Zhao,Jiangyang Lu,Junsheng Ji,Jingmin Zhao +22 more
TL;DR: Circulating cytokines, including IL-8, IL-6, TNF-α, IP10, MCP1, and RANTES, were significantly elevated in patients with severe COVID-19 and could be used to predict disease deterioration and inform clinical interventions.
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Calcineurin Inhibitors Stimulate and Mycophenolic Acid Inhibits Replication of Hepatitis E Virus
Yijin Wang,Xinying Zhou,Yannick Debing,Kan Chen,Kan Chen,Luc J. W. van der Laan,Johan Neyts,Harry L.A. Janssen,Harry L.A. Janssen,Herold J. Metselaar,Maikel P. Peppelenbosch,Qiuwei Pan +11 more
TL;DR: These findings should be considered when physicians select immunosuppressive therapies for recipients of organ transplants who are infected with HEV, and the combination of MPA and ribavirin had a greater ability to inhibit HEV replication than MPA or ribavirus alone.
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Modeling rotavirus infection and antiviral therapy using primary intestinal organoids.
Yuebang Yin,Marcel J. C. Bijvelds,Wen Dang,Lei Xu,Annemiek A. van der Eijk,Karen Knipping,Nesrin Tüysüz,Johanna F. Dekkers,Yijin Wang,Jeroen de Jonge,Dave Sprengers,Luc J. W. van der Laan,Jeffrey M. Beekman,Derk ten Berge,Herold J. Metselaar,Hugo R. de Jonge,Marion Koopmans,Maikel P. Peppelenbosch,Qiuwei Pan +18 more
TL;DR: Human organoids efficiently support the infection of patient-derived rotavirus strains and can be potentially harnessed for personalized evaluation of the efficacy of antiviral medications, providing a robust model system for studying rotav virus-host interactions and assessing antiviral medicines.