Y
Ying Liu
Researcher at York University
Publications - 18
Citations - 1224
Ying Liu is an academic researcher from York University. The author has contributed to research in topics: Adiponectin & Insulin resistance. The author has an hindex of 15, co-authored 18 publications receiving 1115 citations.
Papers
More filters
Journal ArticleDOI
Adiponectin stimulates autophagy and reduces oxidative stress to enhance insulin sensitivity during high fat diet feeding in mice
Ying Liu,Rengasamy Palanivel,Esther Rai,Min Park,Tim V. Gabor,Michael P. Scheid,Aimin Xu,Gary Sweeney +7 more
TL;DR: In summary, adiponectin stimulated skeletal muscle autophagy and antioxidant potential to reduce insulin resistance caused by HFD and overexpressed an inactive mutant of Atg5 to create an Autophagy-deficient cell model, and together with pharmacological inhibition of autphagy, demonstrated reduced insulin sensitivity under these conditions.
Journal ArticleDOI
Adiponectin is expressed by skeletal muscle fibers and influences muscle phenotype and function
Matthew P. Krause,Ying Liu,Vivian Vu,Lawrence Chan,Aimin Xu,Michael C. Riddell,Gary Sweeney,Thomas J. Hawke +7 more
TL;DR: The data demonstrate that the absence of Ad expression causes contractile dysfunction and phenotypical changes in skeletal muscle and that its intramyocellular localization is associated with elevated IMCL, particularly in type IIA/D fibers.
Journal ArticleDOI
Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes
Rengasamy Palanivel,Xiangping Fang,Min Park,Megumi Eguchi,Shelley Pallan,Sabrina De Girolamo,Ying Liu,Yu Wang,Aimin Xu,Gary Sweeney +9 more
TL;DR: These results clearly demonstrate that gAd and fAd mediate distinct and time-dependent effects on cardiomyocyte energy metabolism via AdipoR1 and AdipOR2.
Journal ArticleDOI
Regulation of insulin signalling, glucose uptake and metabolism in rat skeletal muscle cells upon prolonged exposure to resistin.
TL;DR: The data show that resistin regulates the function of IRS-1 and Akt1 and decreases GLUT4 translocation and glucose uptake in response to insulin, highlighting the potential role of resistin in the pathophysiology of type 2 diabetes in obesity.
Journal ArticleDOI
Total and High Molecular Weight But Not Trimeric or Hexameric Forms of Adiponectin Correlate with Markers of the Metabolic Syndrome and Liver Injury in Thai Subjects
Ying Liu,Ravi Retnakaran,Ravi Retnakaran,Anthony J. Hanley,Rungsunn Tungtrongchitr,Collin Shaw,Gary Sweeney +6 more
TL;DR: HMW adiponectin, but not hexameric or trimeric, tracks with the metabolic correlates of total adiponECTin, and an independent inverse association exists between ALT and HMW adip onectin.