Y
Yiran Guo
Researcher at Children's Hospital of Philadelphia
Publications - 97
Citations - 10577
Yiran Guo is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Genome-wide association study & Exome sequencing. The author has an hindex of 33, co-authored 85 publications receiving 8663 citations. Previous affiliations of Yiran Guo include Beijing Genomics Institute & Beijing Institute of Genomics.
Papers
More filters
Journal ArticleDOI
The sequence and de novo assembly of the giant panda genome
Ruiqiang Li,Wei Fan,Geng Tian,Hongmei Zhu,Lin He,Lin He,Jing Cai,Jing Cai,Quanfei Huang,Qingle Cai,Bo Li,Yinqi Bai,Zhihe Zhang,Ya-Ping Zhang,Wen Wang,Jun Li,Fuwen Wei,Heng Li,Min Jian,Jianwen Li,Zhaolei Zhang,Rasmus Nielsen,Dawei Li,Wanjun Gu,Zhentao Yang,Zhaoling Xuan,Oliver A. Ryder,Frederick C. Leung,Yan Zhou,Jianjun Cao,Xiao Sun,Yonggui Fu,Xiaodong Fang,Xiaosen Guo,Bo Wang,Rong Hou,Fujun Shen,Bo Mu,Peixiang Ni,Runmao Lin,Wubin Qian,Guo-Dong Wang,Guo-Dong Wang,Chang Yu,Wenhui Nie,Jinhuan Wang,Zhigang Wu,Huiqing Liang,Jiumeng Min,Qi Wu,Shifeng Cheng,Jue Ruan,Mingwei Wang,Zhongbin Shi,Ming Wen,Binghang Liu,Xiaoli Ren,Huisong Zheng,Dong Dong,Kathleen Cook,Gao Shan,Hao Zhang,Carolin Kosiol,Xueying Xie,Zuhong Lu,Hancheng Zheng,Yingrui Li,Cynthia C. Steiner,Tommy Tsan-Yuk Lam,Siyuan Lin,Qinghui Zhang,Guoqing Li,Jing Tian,Timing Gong,Hongde Liu,Dejin Zhang,Lin Fang,Chen Ye,Juanbin Zhang,Wenbo Hu,Anlong Xu,Yuanyuan Ren,Guojie Zhang,Guojie Zhang,Michael William Bruford,Qibin Li,Lijia Ma,Yiran Guo,Na An,Yujie Hu,Yang Zheng,Yongyong Shi,Zhiqiang Li,Qing Liu,Yanling Chen,Jing Zhao,Ning Qu,Shancen Zhao,Feng Tian,Xiaoling Wang,Haiyin Wang,Lizhi Xu,Xiao Liu,Tomas Vinar,Yajun Wang,Tak-Wah Lam,Siu-Ming Yiu,Shiping Liu,Hemin Zhang,Desheng Li,Yan Huang,Xia Wang,Guohua Yang,Zhi Jiang,Junyi Wang,Nan Qin,Li Li,Jingxiang Li,Lars Bolund,Karsten Kristiansen,Gane Ka-Shu Wong,Maynard V. Olson,Xiuqing Zhang,Songgang Li,Huanming Yang,Jing Wang,Jun Wang +126 more
TL;DR: Using next-generation sequencing technology alone, a draft sequence of the giant panda genome is generated and assembled, indicating that its bamboo diet might be more dependent on its gut microbiome than its own genetic composition.
Journal ArticleDOI
The diploid genome sequence of an Asian individual.
Jun Wang,Wei Wang,Ruiqiang Li,Ruiqiang Li,Yingrui Li,Yingrui Li,Yingrui Li,Geng Tian,Geng Tian,Laurie Goodman,Wei Fan,Junqing Zhang,Jun Li,Juanbin Zhang,Yiran Guo,Yiran Guo,Binxiao Feng,Heng Li,Heng Li,Yao Lu,Xiaodong Fang,Huiqing Liang,Zhenglin Du,Dong Li,Yiqing Zhao,Yiqing Zhao,Yujie Hu,Yujie Hu,Zhenzhen Yang,Hancheng Zheng,Ines Hellmann,Michael Inouye,John E. Pool,Xin Yi,Xin Yi,Jing Zhao,Jinjie Duan,Yan Zhou,Junjie Qin,Junjie Qin,Lijia Ma,Lijia Ma,Guoqing Li,Zhentao Yang,Guojie Zhang,Guojie Zhang,Bin Yang,Chang Yu,Fang Liang,Fang Liang,Wenjie Li,Shaochuan Li,Dawei Li,Peixiang Ni,Jue Ruan,Jue Ruan,Qibin Li,Qibin Li,Hongmei Zhu,Dongyuan Liu,Zhike Lu,Ning Li,Ning Li,Guangwu Guo,Guangwu Guo,Jianguo Zhang,Jia Ye,Lin Fang,Qin Hao,Qin Hao,Quan Chen,Quan Chen,Yu Liang,Yu Liang,Yeyang Su,Yeyang Su,A. san,A. san,Cuo Ping,Cuo Ping,Shuang Yang,Fang Chen,Fang Chen,Li Li,Ke Zhou,Hongkun Zheng,Hongkun Zheng,Yuanyuan Ren,Ling Yang,Yang Gao,Yang Gao,Guohua Yang,Guohua Yang,Zhuo Li,Xiaoli Feng,Karsten Kristiansen,Gane Ka-Shu Wong,Gane Ka-Shu Wong,Rasmus Nielsen,Richard Durbin,Lars Bolund,Lars Bolund,Xiuqing Zhang,Xiuqing Zhang,Songgang Li,Songgang Li,Songgang Li,Huanming Yang,Huanming Yang,Jian Wang,Jian Wang +110 more
TL;DR: Genotyping analysis showed that SNP identification had high accuracy and consistency, indicating the high sequence quality of this assembly, and the potential usefulness of next-generation sequencing technologies for personal genomics.
Journal ArticleDOI
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
Daniel I. Swerdlow,Michael V. Holmes,Karoline Kuchenbaecker,Engmann Jel.,Tina Shah,Reecha Sofat,Yiran Guo,C Chung,Anne Peasey,Roman Pfister,Simon P. Mooijaart,Helen Ireland,Maarten Leusink,Claudia Langenberg,KaWah Li,Jutta Palmen,Phil Howard,Jackie A. Cooper,Fotios Drenos,John Hardy,Mike A. Nalls,Yun Li,Gordon D.O. Lowe,Marlene C. W. Stewart,S. J. Bielinski,Julian Peto,Nicholas J. Timpson,John Gallacher,Malcolm G. Dunlop,Richard S. Houlston,Ian Tomlinson,Ioanna Tzoulaki,Jian'an Luan,Boer Jma.,Nita G. Forouhi,N. C. Onland-Moret,Y. T. van der Schouw,Renate B. Schnabel,Jaroslav A. Hubacek,Růžena Kubínová,Migle Baceviciene,Abdonas Tamosiunas,Andrzej Pajak,Roman Topor-Madry,Sofia Malyutina,Damiano Baldassarre,Bengt Sennblad,Elena Tremoli,U de Faire,Luigi Ferrucci,S Bandenelli,Tetsu Tanaka,James F. Meschia,AB Singleton,Gerjan Navis,I. Mateo Leach,Bakker Sjl.,Ron T. Gansevoort,Ian Ford,Stephen E. Epstein,Mary-Susan Burnett,Joe Devaney,Johan Wouter Jukema,Westendorp Rgj.,G Jan de Borst,Y. van der Graaf,P A de Jong,Mailand-van der Zee A-H.,Olaf H. Klungel,A. de Boer,P. A. Doevendans,Jeffrey W. Stephens,Charles B. Eaton,Jennifer G. Robinson,JoAnn E. Manson,F G Fowkes,Timothy M. Frayling,Jenna Price,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,George Davey Smith,Yoav Ben-Shlomo,Susan Redline,Leslie A. Lange,Meena Kumari,Nicholas J. Wareham,Verschuren Wmm.,Emelia J. Benjamin,John C. Whittaker,Anders Hamsten,Frank Dudbridge,Delaney Jac.,Andrew Wong,Diana Kuh,Rebecca Hardy,Berta Almoguera Castillo,John Connolly,P. van der Harst,Eric J. Brunner,Michael Marmot,Christina L. Wassel,Steve E. Humphries,P.J. Talmud,Mika Kivimäki,Folkert W. Asselbergs,Mikhail I. Voevoda,Martin Bobak,Hynek Pikhart,James G. Wilson,Hakon Hakonarson,Alexander P. Reiner,Brendan J. Keating,Naveed Sattar,Aroon D. Hingorani,Juan P. Casas +115 more
TL;DR: IL6R blockade could provide a novel therapeutic approach to prevention of coronary heart disease that warrants testing in suitably powered randomised trials and could help to validate and prioritise novel drug targets or to repurpose existing agents and targets for new therapeutic uses.
Journal ArticleDOI
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Phil Lee,Verneri Anttila,Hyejung Won,Yen-Chen Anne Feng,Jacob Rosenthal,Zhaozhong Zhu,Elliot M. Tucker-Drob,Michel G. Nivard,Andrew D. Grotzinger,Danielle Posthuma,Meg M.-J. Wang,Dongmei Yu,Eli A. Stahl,Raymond K. Walters,Richard Anney,Laramie E. Duncan,Tian Ge,Rolf Adolfsson,Tobias Banaschewski,Sintia Iole Belangero,Edwin H. Cook,Giovanni Coppola,Eske M. Derks,Pieter J. Hoekstra,Jaakko Kaprio,Anna Keski-Rahkonen,George Kirov,George Kirov,Henry R. Kranzler,Jurjen J. Luykx,Luis Augusto Rohde,Clement C. Zai,Esben Agerbo,Maria Arranz,Philip Asherson,Marie Bækvad-Hansen,Gisli Baldursson,Mark A. Bellgrove,Richard A. Belliveau,Jan K. Buitelaar,Christie L. Burton,Jonas Bybjerg-Grauholm,Miquel Casas,Felecia Cerrato,Kimberly Chambert,Claire Churchhouse,Bru Cormand,Jennifer Crosbie,Søren Dalsgaard,Ditte Demontis,Alysa E. Doyle,Ashley Dumont,Josephine Elia,Jakob Grove,Olafur O Gudmundsson,Jan Haavik,Hakon Hakonarson,Christine Søholm Hansen,Catharina A. Hartman,Ziarih Hawi,Amaia Hervás,David M. Hougaard,Daniel P. Howrigan,Hailiang Huang,Jonna Kuntsi,Kate Langley,Klaus-Peter Lesch,Patrick W. L. Leung,Sandra K. Loo,Joanna Martin,Alicia R. Martin,James J. McGough,Sarah E. Medland,Jennifer L. Moran,Ole Mors,Preben Bo Mortensen,Robert D. Oades,Duncan S. Palmer,Carsten Bøcker Pedersen,Marianne Giørtz Pedersen,Triinu Peters,Timothy Poterba,Jesper Buchhave Poulsen,Josep Antoni Ramos-Quiroga,Andreas Reif,Marta Ribasés,Aribert Rothenberger,Paula Rovira,Cristina Sánchez-Mora,F. Kyle Satterstrom,Russell Schachar,María Soler Artigas,Stacy Steinberg,Hreinn Stefansson,Patrick Turley,G. Bragi Walters,Thomas Werge,Tetyana Zayats,Dan E. Arking,Francesco Bettella,Joseph D. Buxbaum,Jane H. Christensen,Ryan L. Collins,Hilary Coon,Silvia De Rubeis,Richard Delorme,Dorothy E. Grice,Thomas Hansen,Peter Holmans,Sigrun Hope,Christina M. Hultman,Lambertus Klei,Christine Ladd-Acosta,Páll Magnússon,Terje Nærland,Mette Nyegaard,Dalila Pinto,Per Qvist,Karola Rehnström,Abraham Reichenberg,Jennifer Reichert,Kathryn Roeder,Guy A. Rouleau,Evald Saemundsen,Stephen Sanders,Sven Sandin,Beate St Pourcain,Kari Stefansson,James S. Sutcliffe,Michael E. Talkowski,Lauren A. Weiss,A. Jeremy Willsey,Ingrid Agartz,Huda Akil,Diego Albani,Martin Alda,Thomas Damm Als,Adebayo Anjorin,Lena Backlund,Nicholas Bass,Michael Bauer,Bernhard T. Baune,Frank Bellivier,Sarah E. Bergen,Wade H. Berrettini,Joanna M. Biernacka,Douglas Blackwood,Erlend Bøen,Monika Budde,William E. Bunney,Margit Burmeister,William Byerley,Enda M. Byrne,Sven Cichon,Toni-Kim Clarke,Jonathan R. I. Coleman,Nicholas John Craddock,David Curtis,Piotr M. Czerski,Anders M. Dale,Nina Dalkner,Udo Dannlowski,Franziska Degenhardt,Arianna Di Florio,Torbjørn Elvsåshagen,Bruno Etain,Sascha B. Fischer,Andreas J. Forstner,Liz Forty,Josef Frank,Mark A. Frye,Janice M. Fullerton,Katrin Gade,Helena Gaspar,Elliot S. Gershon,Michael Gill,Fernando S. Goes,Scott D. Gordon,Katherine Gordon-Smith,Melissa J. Green,Tiffany A. Greenwood,Maria Grigoroiu-Serbanescu,Jose Guzman-Parra,Joanna Hauser,Martin Hautzinger,Urs Heilbronner,Stefan Herms,Per Hoffmann,Dominic Holland,Stéphane Jamain,Ian Jones,Lisa Jones,Radhika Kandaswamy,John R. Kelsoe,James L. Kennedy,Oedegaard Ketil Joachim,Sarah Kittel-Schneider,Manolis Kogevinas,Anna C. Koller,Catharina Lavebratt,Cathryn M. Lewis,Qingqin S. Li,Jolanta Lissowska,Loes M. Olde Loohuis,Susanne Lucae,Anna Maaser,Ulrik Fredrik Malt,Nicholas G. Martin,Lina Martinsson,Susan L. McElroy,Francis J. McMahon,Andrew McQuillin,Ingrid Melle,Andres Metspalu,Vincent Millischer,Philip B. Mitchell,Grant W. Montgomery,Gunnar Morken,Derek W. Morris,Bertram Müller-Myhsok,Niamh Mullins,Richard M. Myers,Caroline M. Nievergelt,Merete Nordentoft,Annelie Nordin Adolfsson,Markus M. Nöthen,Roel A. Ophoff,Michael John Owen,Sara A. Paciga,Carlos N. Pato,Michele T. Pato,Roy H. Perlis,Amy Perry,James B. Potash,Céline S. Reinbold,Marcella Rietschel,Margarita Rivera,Mary Roberson,Martin Schalling,Peter R. Schofield,Thomas G. Schulze,Laura J. Scott,Alessandro Serretti,Engilbert Sigurdsson,Olav B. Smeland,Eystein Stordal,Fabian Streit,Jana Strohmaier,Thorgeir E. Thorgeirsson,Jens Treutlein,Gustavo Turecki,Arne E. Vaaler,Eduard Vieta,John B. Vincent,Yunpeng Wang,Stephanie H. Witt,Peter P. Zandi,Roger A.H. Adan,Lars Alfredsson,Tetsuya Ando,Harald N. Aschauer,Jessica H. Baker,Vladimir Bencko,Andrew W. Bergen,Andreas Birgegård,Vesna Boraska Perica,Harry Brandt,Roland Burghardt,Laura Carlberg,Matteo Cassina,Maurizio Clementi,Philippe Courtet,Steven Crawford,Scott J. Crow,James J. Crowley,Unna N. Danner,Oliver S. P. Davis,Daniela Degortes,Janiece E. DeSocio,Danielle M. Dick,Christian Dina,Elisa Docampo,Karin Egberts,Stefan Ehrlich,Thomas Espeseth,Fernando Fernández-Aranda,Manfred M. Fichter,Lenka Foretova,Monica Forzan,Giovanni Gambaro,Ina Giegling,Fragiskos Gonidakis,Philip Gorwood,Monica Gratacos Mayora,Yiran Guo,Katherine A. Halmi,Konstantinos Hatzikotoulas,Johannes Hebebrand,Sietske G. Helder,Beate Herpertz-Dahlmann,Wolfgang Herzog,Anke Hinney,Hartmut Imgart,Susana Jiménez-Murcia,Craig Johnson,Jennifer Jordan,Antonio Julià,Deborah Kaminská,Leila Karhunen,Andreas Karwautz,Martien J H Kas,Walter H. Kaye,Martin A. Kennedy,Youl-Ri Kim,Lars Klareskog,Kelly L. Klump,Gun Peggy Knudsen,Mikael Landén,Stephanie Le Hellard,Robert D. Levitan,Dong Li,Paul Lichtenstein,Mario Maj,Sara Marsal,Sara McDevitt,James R. Mitchell,Palmiero Monteleone,Alessio Maria Monteleone,Melissa A. Munn-Chernoff,Benedetta Nacmias,Marie Navratilova,Julie K. O'Toole,Leonid Padyukov,Jacques Pantel,Hana Papezova,Raquel Rabionet,Anu Raevuori,Nicolas Ramoz,Ted Reichborn-Kjennerud,Valdo Ricca,Marion Roberts,Dan Rujescu,Filip Rybakowski,André Scherag,Ulrike Schmidt,Jochen Seitz,Lenka Slachtova,Margarita C T Slof-Op 't Landt,Agnieszka Słopień,Sandro Sorbi,Lorraine Southam,Michael Strober,Alfonso Tortorella,Federica Tozzi,Janet Treasure,Konstantinos Tziouvas,Annemarie A. van Elburg,Tracey D. Wade,Gudrun Wagner,Esther Walton,Hunna J. Watson,H-Erich Wichmann,D. Blake Woodside,Eleftheria Zeggini,Stephanie Zerwas,Stephan Zipfel,Mark Adams,Till F. M. Andlauer,Klaus Berger,Elisabeth B. Binder,Dorret I. Boomsma,Enrique Castelao,Lucía Colodro-Conde,Nese Direk,Anna R. Docherty,Enrico Domenici,Katharina Domschke,Erin C. Dunn,Jerome C. Foo,E.J.C. de Geus,Hans J. Grabe,Steven P. Hamilton,Carsten Horn,Jouke-Jan Hottenga,David M. Howard,Marcus Ising,Stefan Kloiber,Douglas F. Levinson,Glyn Lewis,Patrik K. E. Magnusson,Hamdi Mbarek,Christel M. Middeldorp,Sara Mostafavi,Dale R. Nyholt,Brenda W.J.H. Penninx,Roseann E. Peterson,Giorgio Pistis,David J. Porteous,Martin Preisig,Jorge A. Quiroz,Catherine Schaefer,Eva C. Schulte,Jianxin Shi,Daniel J. Smith,Pippa A. Thomson,Henning Tiemeier,Rudolf Uher,Sandra Van der Auwera,Myrna M. Weissman,Madeline Alexander,Martin Begemann,Elvira Bramon,Nancy G. Buccola,Murray J. Cairns,Dominique Campion,Vaughan J. Carr,C. Robert Cloninger,David Cohen,David A. Collier,Aiden Corvin,Lynn E. DeLisi,Gary Donohoe,Frank Dudbridge,Jubao Duan,Robert B. Freedman,Pablo V. Gejman,Vera Golimbet,Stephanie Godard,Hannelore Ehrenreich,Annette M. Hartmann,Frans Henskens,Masashi Ikeda,Nakao Iwata,Assen Jablensky,Inge Joa,Erik G. Jönsson,Brian Kelly,Jo Knight,Bettina Konte,Claudine Laurent-Levinson,James Lee,Todd Lencz,Bernard Lerer,Carmel M. Loughland,Anil K. Malhotra,Jacques Mallet,Colm McDonald,Marina Mitjans,Bryan J. Mowry,Kieran C. Murphy,Robin M. Murray,F. Anthony O'Neill,Sang-Yun Oh,Aarno Palotie,Christos Pantelis,Ann E. Pulver,Tracey L. Petryshen,Digby Quested,Brien P. Riley,Alan R. Sanders,Ulrich Schall,Sibylle G. Schwab,Rodney J. Scott,Pak C. Sham,Jeremy M. Silverman,Kang Sim,Agnes A. Steixner,Paul A. Tooney,Jim van Os,Marquis P. Vawter,Dermot Walsh,Mark Weiser,Dieter B. Wildenauer,Nigel Williams,Brandon Wormley,Fuquan Zhang,Christos Androutsos,Paul D. Arnold,Cathy L. Barr,Csaba Barta,Katharina Bey,O. Joseph Bienvenu,Donald W. Black,Lawrence W. Brown,Cathy L. Budman,Danielle C. Cath,Keun-Ah Cheon,Valentina Ciullo,Barbara J. Coffey,Daniele Cusi,Lea K. Davis,Damiaan Denys,Christel Depienne,Andrea Dietrich,Valsamma Eapen,Peter Falkai,Thomas V. Fernandez,Blanca Garcia-Delgar,Daniel A. Geller,Donald L. Gilbert,Marco A. Grados,Erica Greenberg,Edna Grünblatt,Julie Hagstrøm,Gregory L. Hanna,Andreas Hartmann,Tammy Hedderly,Gary A. Heiman,Isobel Heyman,Hyun Ju Hong,Alden Y. Huang,Chaim Huyser,Laura Ibanez-Gomez,Ekaterina A. Khramtsova,Young Key Kim,Young Shin Kim,Robert A. King,Yun-Joo Koh,Anastasios Konstantinidis,Sodahm Kook,Samuel Kuperman,Bennett L. Leventhal,Christine Lochner,Andrea G. Ludolph,Marcos Madruga-Garrido,Irene A. Malaty,Athanasios Maras,James T. McCracken,Inge A. Meijer,Pablo Mir,Astrid Morer,Kirsten R. Müller-Vahl,Alexander Münchau,Tara Murphy,Allan L. Naarden,Peter Nagy,Gerald Nestadt,Paul S. Nestadt,Humberto Nicolini,Erika L. Nurmi,Michael S. Okun,Peristera Paschou,Fabrizio Piras,Federica Piras,Christopher Pittenger,Kerstin J. Plessen,Margaret A. Richter,Renata Rizzo,Mary M. Robertson,Veit Roessner,Stephan Ruhrmann,Jack Samuels,Paul Sandor,Monika Schlögelhofer,Eun-Young Shin,Harvey S. Singer,Dong-Ho Song,Jungeun Song,Gianfranco Spalletta,Dan J. Stein,S. Evelyn Stewart,Eric A. Storch,Barbara E. Stranger,Manfred Stuhrmann,Zsanett Tarnok,Jay A. Tischfield,Jennifer Tübing,Frank Visscher,Nienke Vulink,Michael Wagner,Susanne Walitza,Sina Wanderer,Martin Woods,Yulia Worbe,Gwyneth Zai,Samuel H. Zinner,Patrick F. Sullivan,Barbara Franke,Mark J. Daly,Cynthia M. Bulik,Andrew M. McIntosh,Michael Conlon O'Donovan,Amanda B Zheutlin,Ole A. Andreassen,Anders D. Børglum,Gerome Breen,Howard J. Edenberg,Ayman H. Fanous,Stephen V. Faraone,Joel Gelernter,Carol A. Mathews,Manuel Mattheisen,Karen S. Mitchell,Michael C. Neale,John I. Nurnberger,Stephan Ripke,Susan L. Santangelo,Jeremiah M. Scharf,Murray B. Stein,Laura M. Thornton,James T.R. Walters,Naomi R. Wray,Naomi R. Wray,Daniel H. Geschwind,Benjamin M. Neale,Kenneth S. Kendler,Jordan W. Smoller +606 more
TL;DR: Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes.
Journal ArticleDOI
Association between alcohol and cardiovascular disease:Mendelian randomisation analysis based on individual participant data
Michael V. Holmes,Michael V. Holmes,Caroline Dale,Luisa Zuccolo,Richard J. Silverwood,Yiran Guo,Zheng Ye,David Prieto-Merino,Abbas Dehghan,Stella Trompet,Andrew Wong,Alana Cavadino,Dagmar Drogan,Sandosh Padmanabhan,Shanshan Li,Ajay Yesupriya,Maarten Leusink,Johan Sundström,Jaroslav A. Hubacek,Hynek Pikhart,Daniel I. Swerdlow,Andrie G. Panayiotou,S. A. Borinskaya,Chris Finan,Sonia Shah,Karoline Kuchenbaecker,Tina Shah,Jorgen Engmann,Lasse Folkersen,Per Eriksson,Fulvio Ricceri,Olle Melander,Carlotta Sacerdote,Dale M Gamble,Sruti Rayaprolu,Owen A. Ross,Stela McLachlan,OV Vikhireva,Ivonne Sluijs,Robert A. Scott,Vera Adamkova,Leon Flicker,Frank M. van Bockxmeer,Christine Power,Pedro Marques-Vidal,Tom W. Meade,Michael Marmot,José M. Ferro,Sofia Paulos-Pinheiro,Steve E. Humphries,Philippa J. Talmud,Irene Mateo Leach,Niek Verweij,Allan Linneberg,Tea Skaaby,Pieter A. Doevendans,Maarten J Cramer,Pim van der Harst,Olaf H. Klungel,Nicole F. Dowling,Anna F. Dominiczak,Meena Kumari,Andrew N. Nicolaides,Cornelia Weikert,Heiner Boeing,Shah Ebrahim,Tom R. Gaunt,Jackie F. Price,Lars Lannfelt,Anne Peasey,Ruzena Kubinova,Andrzej Pajak,Sofia Malyutina,Mikhail Voevoda,Mikhail Voevoda,Abdonas Tamosiunas,Anke H. Maitland-van der Zee,Paul Norman,Graeme J. Hankey,Graeme J. Hankey,Manuela M. Bergmann,Albert Hofman,Oscar H. Franco,Jackie A. Cooper,Jutta Palmen,Wilko Spiering,Pim A. de Jong,Diana Kuh,Rebecca Hardy,André G. Uitterlinden,M. Arfan Ikram,Ian Ford,Elina Hyppönen,Elina Hyppönen,Osvaldo P. Almeida,Osvaldo P. Almeida,Nicholas J. Wareham,Kay-Tee Khaw,Anders Hamsten,Anders Hamsten,Lise Lotte N. Husemoen,Anne Tjønneland,Janne Schurmann Tolstrup,Eric B. Rimm,Eric B. Rimm,Joline W.J. Beulens,W. M. Monique Verschuren,N. Charlotte Onland-Moret,Marten H. Hofker,S. Goya Wannamethee,Peter H. Whincup,Richard W Morris,Astrid M. Vicente,Hugh Watkins,Hugh Watkins,Martin Farrall,Martin Farrall,J. Wouter Jukema,James F. Meschia,L. Adrienne Cupples,Stephen J. Sharp,Myriam Fornage,Charles Kooperberg,Andrea Z. LaCroix,James Y. Dai,Matthew B. Lanktree,David S. Siscovick,Eric Jorgenson,Bonnie Spring,Josef Coresh,Yun Li,Sarah G. Buxbaum,Pamela J. Schreiner,R. Curtis Ellison,Michael Y. Tsai,Sanjay R. Patel,Sanjay R. Patel,Susan Redline,Andrew D. Johnson,Ron C. Hoogeveen,Hakon Hakonarson,Jerome I. Rotter,Eric Boerwinkle,Paul I.W. de Bakker,Mika Kivimäki,Folkert W. Asselbergs,Folkert W. Asselbergs,Naveed Sattar,Debbie A Lawlor,John C. Whittaker,John C. Whittaker,George Davey Smith,Kenneth J. Mukamal,Bruce M. Psaty,Bruce M. Psaty,James G. Wilson,Leslie A. Lange,Ajna Hamidovic,Aroon D. Hingorani,Børge G. Nordestgaard,Børge G. Nordestgaard,Martin Bobak,David A. Leon,Claudia Langenberg,Tom Palmer,Alexander P. Reiner,Brendan J. Keating,Brendan J. Keating,Frank Dudbridge,Juan P. Casas,Juan P. Casas +170 more
TL;DR: In this article, the causal role of alcohol consumption in cardiovascular disease was investigated using a Mendelian randomisation meta-analysis of 56 epidemiological studies, including 20 259 coronary heart disease cases and 10 164 stroke events.