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Yit Yoong Lim
Researcher at Manchester Academic Health Science Centre
Publications - 36
Citations - 1167
Yit Yoong Lim is an academic researcher from Manchester Academic Health Science Centre. The author has contributed to research in topics: Breast cancer & Mammography. The author has an hindex of 12, co-authored 34 publications receiving 966 citations. Previous affiliations of Yit Yoong Lim include National Health Service & University Hospital of South Manchester NHS Foundation Trust.
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Journal ArticleDOI
Mammographic density adds accuracy to both the Tyrer-Cuzick and Gail breast cancer risk models in a prospective UK screening cohort
Adam R. Brentnall,Elaine F. Harkness,Elaine F. Harkness,Elaine F. Harkness,Susan M. Astley,Susan M. Astley,Susan M. Astley,Louise S Donnelly,Paula Stavrinos,Paula Stavrinos,Sarah Sampson,Lynne Fox,Jamie C. Sergeant,Jamie C. Sergeant,Michelle Harvie,Mary Wilson,Ursula Beetles,Soujanya Gadde,Yit Yoong Lim,Anil Jain,Anil Jain,Anil Jain,Sara Bundred,N Barr,Valerie Reece,Anthony Howell,Jack Cuzick,D. Gareth Evans,D. Gareth Evans +28 more
TL;DR: Breast density may be usefully combined with the Tyrer-Cuzick model or the Gail model in refinement of breast cancer risk estimation.
Journal ArticleDOI
The TOMMY trial: a comparison of TOMosynthesis with digital MammographY in the UK NHS Breast Screening Programme - a multicentre retrospective reading study comparing the diagnostic performance of digital breast tomosynthesis and digital mammography with digital mammography alone.
Fiona J. Gilbert,Lorraine Tucker,Maureen G. C. Gillan,Paula Willsher,Julie Cooke,Karen A Duncan,Michael J Michell,Hilary M Dobson,Yit Yoong Lim,Hema Purushothaman,Celia Strudley,Susan M. Astley,Oliver Morrish,Kenneth C. Young,Stephen W. Duffy +14 more
TL;DR: The specificity of DBT and 2D was better than 2D alone but there was only marginal improvement in sensitivity, and the performance of synthetic 2D appeared to be comparable to standard 2D.
Journal ArticleDOI
Accuracy of Digital Breast Tomosynthesis for Depicting Breast Cancer Subgroups in a UK Retrospective Reading Study (TOMMY Trial)
Fiona J. Gilbert,Lorraine Tucker,Maureen G. C. Gillan,Paula Willsher,Julie Cooke,Karen A Duncan,Michael J Michell,Hilary M Dobson,Yit Yoong Lim,Tamara Suaris,Susan M. Astley,Oliver Morrish,Kenneth C. Young,Stephen W. Duffy +13 more
TL;DR: The addition of DBT increased the sensitivity of 2D mammography in patients with dense breasts and the specificity of 2 D mammography for all subgroups, and the use of synthetic 2D DBT demonstrated performance similar to that of standard 2D Mammography with DBT.
MRI breast screening in high-risk women: cancer detection and survival analysis
D. Gareth Evans,Nisha Kechavan,Yit Yoong Lim,Soujayne Gadde,Emma Hurley,Sarah L Ingham,Rosalind A. Eeles,Howell Anthony,Stephen W. Duffy,Anthony J. Maxwell +9 more
TL;DR: In this article, the authors evaluated whether introduction of MRI surveillance improves 5-and 10-year survival of high-risk women and determine the accuracy of MRI breast cancer detection compared with mammography-only or no enhanced surveillance and compare size and pathology of cancers detected in women screened with MRI + mammography and mammography only.
Journal ArticleDOI
Increased peri-ductal collagen micro-organization may contribute to raised mammographic density.
James C. McConnell,Oliver V. O’Connell,Keith Brennan,Lisa Weiping,Miles Howe,Leena Dennis Joseph,David Knight,Ronan O’Cualain,Yit Yoong Lim,Angela Leek,Rachael Waddington,Jane Rogan,Susan M. Astley,Ashu Gandhi,Cliona C. Kirwan,Michael J. Sherratt,Charles H. Streuli +16 more
TL;DR: Preliminary data suggest that remodelling, and hence stiffening, of the existing stromal collagen microarchitecture promotes high mammographic density within the breast, which may trigger neoplasia-associated mechanotransduction pathways within the epithelial cell population.