Y
Yoh Takuwa
Researcher at Kanazawa University
Publications - 213
Citations - 18880
Yoh Takuwa is an academic researcher from Kanazawa University. The author has contributed to research in topics: Receptor & Vascular smooth muscle. The author has an hindex of 69, co-authored 212 publications receiving 18314 citations. Previous affiliations of Yoh Takuwa include Boston University & University of Tsukuba.
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Journal ArticleDOI
Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor.
Takeshi Sakurai,Masashi Yanagisawa,Yoh Takuwa,Hitoshi Miyazaki,Sadao Kimura,Katsutoshi Goto,Tomoh Masaki +6 more
TL;DR: The cloning of a complementary DNA encoding one subtype belonging to the superf amily of G protein-coupled receptors is reported, indicating that this cDNA encodes a 'nonselective' subtype of the receptor which is different from the vascular smooth muscle receptor.
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A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.
TL;DR: The cloning of the complementary DNA encoding a cell-surface LTB4 receptor that is highly expressed in human leukocytes is reported, showing that L TB4 is a unique lipid mediator that interacts with both cell- surface and nuclear receptors.
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Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils.
Jingsong Xu,Fei Wang,Alexandra Van Keymeulen,Alexandra Van Keymeulen,Paul Herzmark,Aaron F. Straight,Kathleen Kelly,Yoh Takuwa,Naotoshi Sugimoto,Timothy J. Mitchison,Henry R. Bourne +10 more
TL;DR: Like neutrophilic leukocytes, differentiated HL-60 cells respond to chemoattractant by adopting a polarized morphology, with F-actin in a protruding pseudopod at the leading edge and contractile actin-myosin complexes at the back and sides.
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Protein kinase C in the regulation of smooth muscle contraction.
TL;DR: A new model of smooth muscle contraction is proposed that differs radically from accepted views, particularly the latch bridge hypothesis, in terms of both Ca2+ messenger function and the molecular events underlying this process.
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A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts
TL;DR: The results indicate that the inositol lipid signaling pathway plays an important role in endothelin-induced mitogenesis in Swiss 3T3 fibroblasts, and that differences in the signal generation may contribute to the differences in potencies between the two mitogens.