Y
Yohko Nakahara
Researcher at Mitsubishi
Publications - 2
Citations - 3744
Yohko Nakahara is an academic researcher from Mitsubishi. The author has contributed to research in topics: Mutant & Autophagy database. The author has an hindex of 2, co-authored 2 publications receiving 3440 citations.
Papers
More filters
Journal ArticleDOI
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara,Kenji Nakamura,Makoto Matsui,Makoto Matsui,Makoto Matsui,Akitsugu Yamamoto,Yohko Nakahara,Rika Suzuki-Migishima,Minesuke Yokoyama,Kenji Mishima,Ichiro Saito,Hideyuki Okano,Noboru Mizushima +12 more
TL;DR: The results suggest that the continuous clearance of diffuse cytosolic proteins through basal autophagy is important for preventing the accumulation of abnormal proteins, which can disrupt neural function and ultimately lead to neurodegeneration.
Journal ArticleDOI
A Single Amino Acid Mutation in SNAP-25 Induces Anxiety-Related Behavior in Mouse
Masakazu Kataoka,Saori Yamamori,Eiji Suzuki,Shigeru Watanabe,Taku Sato,Hitoshi Miyaoka,Sadahiro Azuma,Shiro Ikegami,Reiko Kuwahara,Rika Suzuki-Migishima,Yohko Nakahara,Itsuko Nihonmatsu,Kaoru Inokuchi,Yuko Katoh-Fukui,Minesuke Yokoyama,Masami Takahashi +15 more
TL;DR: Results clearly indicate that PKC-dependent SNAP-25 phosphorylation plays a critical role in the regulation of emotional behavior as well as the suppression of epileptic seizures, and the lack of enhancement of monoamine release is one of the possible mechanisms underlying these defects.