Yuming Yang,†,§ Qiang Zhao,‡,§ Wei Feng,† and Fuyou Li*,† †Department of Chemistry and State Key Laboratory of Molecular Engineering of Polymers and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, P. R. China ‡Key Laboratory for Organic Electronics and Information Displays (KLOEID) and Institute of Advanced Materials (IAM), Nanjing University of Posts and Telecommunications, Nanjing 210046, P. R. China.

Luminescent chemodosimeters for bioimaging.

The brain is a singular organ of unique biological complexity that serves as the command center for cognitive and motor function. As such, this specialized system also possesses a unique chemical composition and reactivity at the molecular level. In this regard, two vital distinguishing features of the brain are its requirements for the highest concentrations of metal ions in the body and the highest per-weight consumption of body oxygen. In humans, the brain accounts for only 2% of total body mass but consumes 20% of the oxygen that is taken in through respiration. As a consequence of high oxygen demand and cell complexity, distinctly high metal levels pervade all regions of the brain and central nervous system. Structural roles for metal ions in the brain and the body include the stabilization of biomolecules in static (e.g., Mg2+ for nucleic acid folds, Zn2+ in zinc-finger transcription factors) or dynamic (e.g., Na+ and K+ in ion channels, Ca2+ in neuronal cell signaling) modes, and catalytic roles for brain metal ions are also numerous and often of special demand.

Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging

Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives Xiaoqiang Chen, Tuhin Pradhan, Fang Wang, Jong Seung Kim,* and Juyoung Yoon* Departments of Chemistry and Nano Science and of Bioinspired Science (WCU), Ewha Womans University, Seoul 120-750, Korea State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing University of Technology, Nanjing 210009, China Department of Chemistry, Korea University, Seoul 136-701, Korea

Fluorescent chemosensors based on spiroring-opening of xanthenes and related derivatives.

Design strategies for water-soluble small molecular chromogenic and fluorogenic probes.

This tutorial review focuses on the recent development of rhodamine derivatives, in which the spirolactam (non-fluorescent) to ring-opened amide (fluorescent) process was utilized.

A new trend in rhodamine-based chemosensors: application of spirolactam ring-opening to sensing ions

New fluorescent rhodamine hydrazone chemosensor for Cu(II) with high selectivity and sensitivity.

Copper-catalyzed ortho-acylation of phenols with aryl aldehydes and its application in one-step preparation of xanthones.

A new dual-responsive organogel based on uracil-appended glycyrrhetinic acid.

http://www.rsc.org/suppdata/cc/c2/c2cc16921e/c2cc16921e.pdf

Yong Ju

Papers

New fluorescent rhodamine hydrazone chemosensor for Cu(II) with high selectivity and sensitivity.

Copper-catalyzed ortho-acylation of phenols with aryl aldehydes and its application in one-step preparation of xanthones.

A new dual-responsive organogel based on uracil-appended glycyrrhetinic acid.

Visible light-responsive micelles formed from dialkoxyanthracene-containing block copolymers

AIE-induced fluorescent vesicles containing amphiphilic binding pockets and the FRET triggered by host–guest chemistry