Yong Lin

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: Nuclear factor kappa B is involved in cancer development, modulating NF-κB activation pathways has important implications in cancer prevention and therapy.

TL;DR: It is shown that MAPK–ERK kinase kinase (MEKK3) is an essential signal transducer of the MyD88–IRAK–TRAF6 complex in IL-1R–TLR4 signaling.

TL;DR: Evidence is provided showing a critical role of reactive oxygen species (ROS) accumulation induced by luteolin in modulating TNF-activated pathways in lung cancer cells and suggesting that the accumulation of ROS induced byluteolin plays a pivotal role in suppression of NF-κB and potentiated the c-Jun N-terminal kinase to sensitize Lung cancer cells to undergo T NF-induced apoptosis.