Y
Yongbing Liu
Researcher at Indiana University – Purdue University Indianapolis
Publications - 12
Citations - 578
Yongbing Liu is an academic researcher from Indiana University – Purdue University Indianapolis. The author has contributed to research in topics: Catalysis & Chemistry. The author has an hindex of 4, co-authored 6 publications receiving 509 citations.
Papers
More filters
Journal ArticleDOI
Site-selective C–H arylation of primary aliphatic amines enabled by a catalytic transient directing group
Yongbing Liu,Haibo Ge +1 more
TL;DR: The direct, highly site-selective γ-arylation of primary alkylamines via a palladium-catalysed C–H bond functionalization process on unactivated sp3 carbons is reported and is demonstrated in the synthesis of analogues of the immunomodulatory drug fingolimod directly from commercially available 2-amino-2-propylpropane-1,3-diol.
Journal ArticleDOI
Catalytic C–H Arylation of Aliphatic Aldehydes Enabled by a Transient Ligand
TL;DR: The direct arylation of aliphatic aldehydes has been established via Pd-catalyzed sp3 C-H bond functionalization in the presence of 3-aminopropanoic acids as transient directing groups thanks to excellent functional group compatibility and chemoselectivity.
Site-Selective C−H Arylation of Primary Aliphatic Amines Enabled by a Catalytic Transient Directing Group
Yongbing Liu,Haibo Ge +1 more
TL;DR: In this article, a palladium-catalysed γ-arylation of primary alkylamines is achieved using an inexpensive, catalytic and transient directing group, which can be used to accelerate the transition-metal-catalyzed direct C(sp3)−H functionalization.
Journal ArticleDOI
Palladium-catalyzed ligand-promoted site-selective cyanomethylation of unactivated C(sp3)-H bonds with acetonitrile.
TL;DR: The direct coupling of unactivated sp3 C–H bonds in aliphatic amides with acetonitrile was achieved via palladium catalysis.