Author
Yoo Tanabe
Other affiliations: Shinshu University, Sumitomo Chemical
Bio: Yoo Tanabe is an academic researcher from Kwansei Gakuin University. The author has contributed to research in topics: Silylation & Claisen condensation. The author has an hindex of 31, co-authored 205 publications receiving 2760 citations. Previous affiliations of Yoo Tanabe include Shinshu University & Sumitomo Chemical.
Topics: Silylation, Claisen condensation, Aldol reaction, Enol, Ketene
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors used Diphenylammonium triflate (DPAT) as a catalyst for esterification between equimolar amounts of carboxylic acids and alcohols in good yields under mild reaction conditions.
144 citations
TL;DR: In this article, TsCl / Et3N (1.5-2.5 equiv) / cat. Me3N·HCl (0.1-1.0 equiv), KOH [or Ca(OH)2]/Cat.
137 citations
TL;DR: A pentafluorophenylammonium triflate (PFPAT) catalyst was used in this paper to promote esterification and thioesterification between a 1 : 1 mixture of carboxylic acids and alcohols or thiols.
96 citations
90 citations
TL;DR: Ti-crossed-Claisen condensation between a 1:1 mixture of carboxylic esters and acid chlorides promoted by TiCl4-Bu3N-N-methylimidazole proceeded successfully to give various beta-keto esters in good yields with excellent selectivities.
Abstract: Ti-crossed-Claisen condensation between a 1:1 mixture of carboxylic esters and acid chlorides promoted by TiCl4−Bu3N-N-methylimidazole proceeded successfully to give various β-keto esters in good yields with excellent selectivities (19 examples, ∼48−95% yield; cross/self-selectivity = ∼96/4−99/1). The present method was extended to the condensation between a 1:1 mixture of carboxylic acids and carboxylic esters (six examples, ∼70−92% yield; cross/self-selectivity = ∼91/9−99/1). To demonstrate the utility of the present two Ti-crossed-Claisen condensations, we performed a couple of efficient short-step syntheses of two natural, representative, and useful perfumes, cis-jasmone and (R)-muscone.
84 citations
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TL;DR: Dehydroisomerization of Limonene and Terpenes To Produce Cymene 2481 4.2.1.
Abstract: 3.2.3. Hydroformylation 2467 3.2.4. Dimerization 2468 3.2.5. Oxidative Cleavage and Ozonolysis 2469 3.2.6. Metathesis 2470 4. Terpenes 2472 4.1. Pinene 2472 4.1.1. Isomerization: R-Pinene 2472 4.1.2. Epoxidation of R-Pinene 2475 4.1.3. Isomerization of R-Pinene Oxide 2477 4.1.4. Hydration of R-Pinene: R-Terpineol 2478 4.1.5. Dehydroisomerization 2479 4.2. Limonene 2480 4.2.1. Isomerization 2480 4.2.2. Epoxidation: Limonene Oxide 2480 4.2.3. Isomerization of Limonene Oxide 2481 4.2.4. Dehydroisomerization of Limonene and Terpenes To Produce Cymene 2481
5,127 citations
1,248 citations
TL;DR: In this paper, the authors present an overview of the relationship between organic chemistry and natural products, focusing on the Stereochemistry and the Chemistry of Natural Products (SCHP).
Abstract: Organic Chemistry By Dr. I. L. Finar. Vol. 2: Stereochemistry and the Chemistry of Natural Products. Pp. xi + 733. (London and New York: Longmans, Green and Co., Ltd., 1956.) 40s. net.
1,037 citations
TL;DR: This Review classifies strategies in the asymmetric synthesis of axially chiral biaryl compounds according to their underlying concepts and critically evaluates their scope and limitations with reference to selected model reactions and applications.
Abstract: A rotationally hindered and thus stereogenic biaryl axis is the structurally and stereochemically decisive element of a steadily growing number of natural products, chiral auxiliaries, and catalysts. Thus, it is not surprising that significant advances have been made in the asymmetric synthesis of axially chiral biaryl compounds over the past decade. In addition to the classic approach (direct stereoselective aryl-aryl coupling), innovative concepts have been developed in which the asymmetric information is introduced into a preformed, but achiral-that is, symmetric or configurationally labile-biaryl compound, or in which an aryl--C single bond is stereoselectively transformed into an axis. This Review classifies these strategies according to their underlying concepts and critically evaluates their scope and limitations with reference to selected model reactions and applications. Furthermore, the preconditions required for the existence of axial chirality in biaryl compounds are discussed.
985 citations
TL;DR: The present article addresses the radical trifluoromethylation of alkenes and arenes mainly focussing on recent achievements, however, important earlier work in this field is also covered.
Abstract: This Minireview highlights recent developments in radical trifluoromethylation reactions. The trifluoromethyl group belongs to the privileged moieties in medicinal chemistry. Many drugs and drug candidates contain a trifluoromethyl substituent. Also in agrochemicals, the CF3 moiety often appears. The present article addresses the radical trifluoromethylation of alkenes and arenes mainly focussing on recent achievements. However, important earlier work in this field is also covered.
835 citations