Author
Yoshiko Fujii
Bio: Yoshiko Fujii is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Nociception & Somatosensory evoked potential. The author has an hindex of 1, co-authored 1 publications receiving 16 citations.
Papers
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TL;DR: Under the experimental system in the present study, electrical median nerve stimulation as conditioning stimulation significantly decreased both the SEP amplitude induced by electrical tooth simulation and subjective pain expressed by the VAS.
16 citations
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TL;DR: On the basis of the findings of this inquiry, specific diagnostic terms for pulpal health and disease are suggested.
160 citations
TL;DR: Heterotopic ischemic stimulation attenuated the late component of SEP induced by electrical tooth stimulation, triggering diffuse noxious inhibitory controls (DNIC) and after‐effects in the trigeminal nerve territory.
68 citations
TL;DR: Systemic administration of dexmedetomidine (DEX; selective α2‐adrenoceptor agonist) is found to inhibit diffuse noxious inhibitory control in rats, now referred to as conditioned pain modulation (CPM) in humans.
42 citations
TL;DR: The result indicated that selective Aδ‐fiber stimulation with the CO2 laser produces aDNIC effect in the trigeminal nerve territory and suggested that the DNIC effect does not depend on the intensity of the test stimuli.
Abstract: The purpose of this study was to investigate (1) whether selective A δ -fiber stimulation with CO 2 laser produces a diffuse noxious inhibitory controls (DNIC) effect in the trigeminal nerve territory; and (2) whether the DNIC effect differs depending on test stimulus intensities under constant conditioning stimuli To examine whether the CO 2 laser radiation on the dorsum of the hand selectively stimulates A δ -fibers, laser evoked potentials (LEP) were recorded The mean peak latency of LEP was 3814 ms The findings revealed that the CO 2 laser selectively stimulated A δ -fibers Electrical tooth stimuli with 3 levels of intensities (12, 14, 16 times the pain threshold) were applied to subjects as test stimulation in randomized order, with a CO 2 laser stimulus of 18 mJ/mm 2 applied to the dorsum of the hand for 4 min as the noxious conditioning stimulus Somatosensory evoked potentials (SEP) induced by electrical tooth stimulation were recorded and tooth pain intensity was evaluated using a visual analogue scale (VAS) The amplitudes of the SEP late component and VAS values were significantly decreased only during the conditioning stimuli without aftereffect The inhibitory rates of the amplitudes ranged from 313% to 346% and the VAS values from 290% to 312% There were no significant differences in their inhibitory rates between the 3 test stimulus intensities The result indicated that selective A δ -fiber stimulation with the CO 2 laser produces a DNIC effect in the trigeminal nerve territory and suggested that the DNIC effect does not depend on the intensity of the test stimuli
29 citations