Author
Yoshinobu Inouye
Other affiliations: University of Tokushima
Bio: Yoshinobu Inouye is an academic researcher from University of Tsukuba. The author has contributed to research in topics: Allylic rearrangement & Bicyclic molecule. The author has an hindex of 14, co-authored 73 publications receiving 772 citations. Previous affiliations of Yoshinobu Inouye include University of Tokushima.
Papers published on a yearly basis
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TL;DR: In this paper, the stereochemistry of the cembranolides isolated from the soft coral Sinularia mayi has been elucidated by means of 2D NMR spectroscopy and X-ray crystallography.
123 citations
TL;DR: In this article, modified Mosher's method has been extended by use of 9-anthranylmethoxyacetic acid (9ATMA) and 2-naphthylmethoxynaphthymethylacetic acids (2NMA) instead of MTPA of the conventional method.
81 citations
TL;DR: In this article, the effect of substituents for orientation phenomena can be considered to be of electronic nature, and preliminary accounts for the Diels-Alder reaction of methoxybenzoquinone revealed that the effect on orientation properties can be assumed to be electronic.
Abstract: Total syntheses of tanshinone-II (II) and cryptotanshinone (III) from 3-methylbenzofuran-4, 7-quinone (X) and 6,6-dimethyl-l-vinylcyclohexene (IX), and of tanshinone-I (I) from quinone X and o-methylstyrene (XVIII) are described. Preliminary accounts for the Diels-Alder reaction of methoxybenzoquinone revealed that the effect of substituents for orientation phenomena can be considered to be of electronic nature.
37 citations
TL;DR: Fluvirucin A1 was established as (2R,3S,6R, 10S)-3-[(3-amino-3, 6-dideoxy-alpha-L-talopyranosyl)-oxy]-2,6-dimethyl-10 -ethyl-13-tridecanelactam by chemical, spectroscopic, and X-ray crystallographic analyses.
Abstract: Fluvirucin A1 was established as (2R,3S,6R, 10S)-3-[(3-amino-3,6-dideoxy-alpha-L-talopyranosyl)-oxy]-2,6-dimethyl-10 -ethyl-13-tridecanelactam by chemical, spectroscopic, and X-ray crystallographic analyses.
32 citations
31 citations
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TL;DR: This review covers the literature published in 2014 for marine natural products, with 1116 citations referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms.
4,649 citations
TL;DR: In this paper, the application of (S)-1,10-binaphthyl-2,20-diol as NMR chiral solvating agent (CSA) for omeprazole, and three of its analogs (lanso-, panto-, and rabe-prazole) was investigated.
Abstract: The application of (S)-1,10-binaphthyl-2,20-diol as NMR chiral solvating agent (CSA) for omeprazole, and three of its analogs (lanso-, panto-, and rabe-prazole) was investigated. The formation of diastereomeric host–guest complexes in solution between the CSA and the racemic substrates produced sufficient NMR signal splitting for the determination of enantiomeric excesses by Hor F-NMR spectroscopy. Using of hydrophobic deuterated solvents was mandatory for obtaining good enantiodiscrimination, thus suggesting the importance of intermolecular hydrogen bonds in the stabilization of the complexes. The method was applied to the fast quantification of the enantiomeric purity of in-process samples of S-omeprazole. Chirality 00:000–000, 2009. VC 2009
885 citations
TL;DR: In this review, it is attempted to cover all recent aspects of [2 + 2] photocycloaddition chemistry with an emphasis on synthetically relevant, regio-, and stereoselective reactions.
Abstract: The [2 + 2] photocycloaddition is undisputedly the most important and most frequently used photochemical reaction. In this review, it is attempted to cover all recent aspects of [2 + 2] photocycloaddition chemistry with an emphasis on synthetically relevant, regio-, and stereoselective reactions. The review aims to comprehensively discuss relevant work, which was done in the field in the last 20 years (i.e., from 1995 to 2015). Organization of the data follows a subdivision according to mechanism and substrate classes. Cu(I) and PET (photoinduced electron transfer) catalysis are treated separately in sections 2 and 4, whereas the vast majority of photocycloaddition reactions which occur by direct excitation or sensitization are divided within section 3 into individual subsections according to the photochemically excited olefin.
646 citations
TL;DR: The most important photochemical transformations that have been employed in natural product synthesis are presented and selected total syntheses are discussed as examples, with particular attention given to the photochemical key step and its stereoselectivity.
Abstract: Photochemical reactions contribute in a significant way to the existing repertoire of carbon-carbon bond-forming reactions by allowing access to exceptional molecular structures that cannot be obtained by conventional means. In this Review, the most important photochemical transformations that have been employed in natural product synthesis are presented. Selected total syntheses are discussed as examples, with particular attention given to the photochemical key step and its stereoselectivity. The structural relationship between the photochemically generated molecule and the natural product is shown, and, where necessary, the consecutive reactions in the synthesis are illustrated and classified.
605 citations
554 citations