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Author

Yoshitoshi Ito

Other affiliations: Tokai University
Bio: Yoshitoshi Ito is an academic researcher from Hitachi. The author has contributed to research in topics: Signal & Light intensity. The author has an hindex of 20, co-authored 79 publications receiving 2285 citations. Previous affiliations of Yoshitoshi Ito include Tokai University.


Papers
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Journal ArticleDOI
TL;DR: It was found that the regional change in cerebral blood volume in the primary motor area overlaps the global change around the motor cortex.
Abstract: The effect of motor activity on the left fronto‐central region of the human brain was analyzedspatially and temporally by using noninvasive near‐infrared light (NIR) topography. The changes in oxygenation states caused by motor activity were measured using intensity‐modulated NIR spectroscopy at ten measurement positions on the head surface. The subject randomly performed unilateral finger opposition for 30 s as motor stimulation. When the subject performed contralateral (right) finger movement, significant increases in both oxygenated hemoglobin (oxy‐Hb) and total hemoglobin (total‐Hb) and decreases in deoxygenated hemoglobin (deoxy‐Hb) were observed in a particular area. By mapping the static topograms of the changes of each Hb and comparing them with an anatomical image of MRI, it was found that the particular area was located on the motor cortex along the central sulcus. By mapping the dynamic topograms of the changes of total‐Hb, which reflect the cerebral blood volume, and analyzing the spatiotemporal hemodynamic changes associated with the brain activity, it was found that the regional change in cerebral blood volume in the primary motor area overlaps the global change around the motor cortex. These results demonstrate that NIR topography can be used to effectively observe the human brain activity.

706 citations

Journal ArticleDOI
Eiju Watanabe, Yuichi Yamashita1, Atsushi Maki1, Yoshitoshi Ito1, Hideaki Koizumi1 
TL;DR: Functional brain mapping is described using multi channel (ten channel) NIRS by applying the motor stimulation in humans to demonstrate that the regional hemodynamic change was detected in a small area around the motor cortex with a time resolution of 1-2 s.

212 citations

Journal ArticleDOI
TL;DR: The concept of noninvasive trans-cranial dynamic optical topography and its instrumentation is described and the validity of this method is confirmed after it was applied to a wide variety of fields such as clinical medicine, cognitive science, and linguistics.
Abstract: Near-infrared spectroscopy is discussed from the viewpoint of human higher-order brain function analysis. Pioneering work in this field is reviewed; then we describe our concept of noninvasive trans-cranial dynamic optical topography and its instrumentation. Also, the validity of its functional images is assessed from both physical and physiological viewpoints. After confirming the validity of this method, we have applied it to a wide variety of fields such as clinical medicine, cognitive science, and linguistics in collaboration with researchers at several other institutes. Further application possibilities and the future of trans-cranial dynamic optical topography are also discussed. © 1999 Society of Photo-Optical Instrumentation Engineers.

160 citations

Journal ArticleDOI
TL;DR: The functional topography of human brain activity due to motor stimulation by using near-infrared spectroscopy is described and a greater change inoxyhemoglobin concentration due to brain activity during the stimulation was obtained for the right hand than for the left hand.
Abstract: Yuichi YamashitaAtsushi MakiYoshitoshi ItoHitachi Ltd.Central Research LaboratoryKokubunji, Tokyo 185, JapanE-mail: yu-yama@crl.hitachi.co.jpEiju WatanabeYoshiaki MayanagiTokyo Metropolitan Police HospitalDepartment of NeurosurgeryTokyo 102, JapanHideaki KoizumiHitachi Ltd.Central Research LaboratoryKokubunji, Tokyo 185, JapanAbstract. We describe the functional topography of human brain activitydue to motor stimulation by using near-infrared spectroscopy. Finger mo-tion by each hand was used as the motor stimulation, and activity in theleft fronto-central region of the brain was measured. A greater change inoxyhemoglobin concentration due to brain activity during the stimulationwas obtained for the right hand than for the left hand. Localization of theactivity was obtained by topographically mapping the measured changesfor ten positions within the region. © 1996 Society of Photo-OpticalInstrumentation Engineers.

105 citations

Patent
23 Aug 2007
TL;DR: In this article, a personal identification system was proposed, which uses a vein pattern of a finger, optimizes the amount of light of a light source based on a captured finger image and emphasizes the vein pattern during image processing for identification.
Abstract: A personal identification system, which uses a vein pattern of a finger, optimizes the amount of light of a light source based on a captured finger image and emphasizes the vein pattern during image processing for identification.

88 citations


Cited by
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Patent
14 Jul 2011
TL;DR: By using a multiple receiving coil composed of receiving coils, an imaging portion of a subject is subjected to a first pulse sequence to create n sensitivity images (701 to 703) fewer than the examination images as discussed by the authors.
Abstract: By using a multiple receiving coil composed of receiving coils, an imaging portion of a subject is subjected to a first pulse sequence to create n sensitivity images (701 to 703) fewer than the examination images. When these sensitivity images are created, an NMR signal is measured for only the low-frequency region of the k space. A second pulse sequence from which a phase encode step is removed is conducted to create m (m>n) examination images (704, 705) of the subject by using the receiving coils. When sensitivity distributions (707, 708) of the receiving coils are determined for the sensitivity images (701 to 703), and if there are no sensitivity distributions corresponding to the slice positions of the examination images (704, 705), they are determined by slice interpolation using the sensitivity distributions (701 to 703), and the aliasing artifacts of the examination images (704, 705) are removed by matrix operation by using the sensitivity distributions (707, 708).

1,792 citations

Journal ArticleDOI
TL;DR: A brief historical overview of the events that have shaped the present status of fNIRS is presented, including the introduction of the commercial multi-channel systems, recent commercial wireless instrumentation and more advanced prototypes.

1,637 citations

Journal ArticleDOI
TL;DR: First near-infrared imaging devices are being applied successfully for low-resolution functional brain imaging andvantages of the optical methods include biochemical specificity, a temporal resolution in the millisecond range, the potential of measuring intracellular and intravascular events simultaneously and the portability of the devices enabling bedside examinations.

1,602 citations

Journal ArticleDOI
TL;DR: The aim of this publication is to review the current state of instrumentation and methodology of continuous wave fNIRI, and provides an overview of the commercially available instruments and address instrumental aspects such as light sources, detectors and sensor arrangements.

1,333 citations

Patent
24 Oct 2006
TL;DR: In this article, a support structure for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of the parameters.
Abstract: Support structures for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of the parameters. The support structure includes a sensor fitted on the support structures using a special geometry for acquiring continuous and undisturbed data on the physiology of the body. Signals are transmitted to a remote station by wireless transmission such as by electromagnetic waves, radio waves, infrared, sound and the like or by being reported locally by audio or visual transmission. The physical and chemical parameters include brain function, metabolic function, hydrodynamic function, hydration status, levels of chemical compounds in the blood, and the like. The support structure includes patches, clips, eyeglasses, head mounted gear and the like, containing passive or active sensors positioned at the end of the tunnel with sensing systems positioned on and accessing a physiologic tunnel.

1,147 citations