Y
Young Il Yeom
Researcher at University of Texas at Austin
Publications - 6
Citations - 1234
Young Il Yeom is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 6, co-authored 6 publications receiving 1202 citations. Previous affiliations of Young Il Yeom include European Bioinformatics Institute & National Institutes of Health.
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Journal ArticleDOI
Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells
Young Il Yeom,Guy Fuhrmann,Catherine E. Ovitt,Alexander Brehm,Kazuyuki Ohbo,Michael K. Gross,Karin Hübner,Hans R. Schöler +7 more
TL;DR: Oct-4 expression in the germline is regulated separately from epiblast expression, and this provides the first marker for the identification of totipotent cells in the embryo, and suggests that expression of Oct-4 in the Totipotent cycle is dependent on a set of factors unique to the germ line.
Journal ArticleDOI
Structure, expression and chromosomal location of the Oct-4 gene.
TL;DR: The genomic structure and sequence ofOct-4 determined in t-haplotypes reveals five exons, and shows no significant changes in the t12 mutant haplotype making it unlikely that Oct-4 and the t 12 early embryonic lethal are the same gene.
Journal ArticleDOI
Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo.
Saverio Minucci,Valérie Botquin,Young Il Yeom,Anup Dey,Ian Sylvester,Dina J. Zand,Kazuyuki Ohbo,Keiko Ozato,Hans R. Schöler +8 more
TL;DR: The partial factor displacement seen in F9 EC cells, combined with the observation that EC and ES cells utilize the proximal and distal enhancers in differential manner, indicate the complex pattern of Oct3/4 gene regulation, which could reflect a cell type‐ and lineage‐specific expression of the gene in vivo.
Journal ArticleDOI
Testis-/embryo-expressed genes are clustered in the mouse H-2K region
TL;DR: A molecular genetic approach was used to study the detailed genomic structure of 240 kilobases surrounding the H-2K gene and 150 kb of a partly homologous region located in the distal inversion of the t complex, found to contain an impressively high density of genes.
Journal ArticleDOI
Several testis-expressed genes in the mouse t-complex have expression differences between wild-type and t-mutant mice
Hae-Sook Ha,C. Alan Howard,Young Il Yeom,Kuniya Abe,Hiroshi Uehara,Karen Artzt,Dorothea Bennett +6 more
TL;DR: Seven genes, which are expressed in the germ cells of testis and map to various regions of the t-complex of the mouse, are identified and imply that Tctex genes might be candidate genes for sterility or TRD.