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Young-Si Jun

Bio: Young-Si Jun is an academic researcher. The author has contributed to research in topics: Succinic acid & Extraction (chemistry). The author has an hindex of 1, co-authored 1 publications receiving 23 citations.

Papers
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01 Jan 2005
TL;DR: In this paper, the intrinsic kinetics of succinic acid from aqueous solution with 1-octanol solutions of tri-n-octylamine (TOA) were carried out using a stirred cell with a microporous hydrophobic membrane.
Abstract: Kinetic studies for the extraction of succinic acid from aqueous solution with 1‐octanol solutions of tri‐n‐octylamine (TOA) were carried out using a stirred cell with a microporous hydrophobic membrane. The interfacial concentrations of species were correlated and thus the intrinsic kinetics was obtained. The overall extraction process was controlled by the chemical reaction at or near the interface between the aqueous and organic phases. The formation reaction of succinic acid‐TOA complex was found to be first order with respect to the concentration of succinic acid in the aqueous phase and the order of 0.5 with respect to that of TOA in the organic phase with a rate constant of (3.14 ± 0.6) × 10−8 m2.5·mol−0.5·s−1. The dissociation reaction of succinic acid‐TOA complex was found to be the second‐order with respect to that of succinic acid‐TOA complex in the organic phase and the order of –2 with respect to that of TOA in the organic phase with a rate constant of (1.44 ± 1.4) × 10−4 mol·m−2·s−1.

24 citations


Cited by
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Journal ArticleDOI
TL;DR: In-situ removal of carboxylic acid by extraction during fermentation is the most popular approach, but recovery of the extractant can easily lead to waste inorganic salt formation, which counteracts the advantage of the in-Situ removal.

379 citations

Journal ArticleDOI
TL;DR: This review focuses on the engineering of Escherichia coli for the production of four‐carbon dicarboxylic acid and the costs of the overall biorefinery‐compatible process will determine the economic commercialization of succinate and its impact in larger chemical markets.
Abstract: Succinate has been recognized as an important platform chemical that can be produced from biomass. While a number of organisms are capable of succinate production naturally, this review focuses on the engineering of Escherichia coli for the production of four-carbon dicarboxylic acid. Important features of a succinate production system are to achieve an optimal balance of reducing equivalents generated by consumption of the feedstock, while maximizing the amount of carbon channeled into the product. Aerobic and anaerobic production strains have been developed and applied to production from glucose and other abundant carbon sources. Metabolic engineering methods and strain evolution have been used and supplemented by the recent application of systems biology and in silico modeling tools to construct optimal production strains. The metabolic capacity of the production strain, the requirement for efficient recovery of succinate, and the reliability of the performance under scaleup are important in the overall process. The costs of the overall biorefinery-compatible process will determine the economic commercialization of succinate and its impact in larger chemical markets.

167 citations

Journal ArticleDOI
TL;DR: A review on reactive extraction of carboxylic acids from fermentation broths is presented in this article, where reactive extraction is found to be a capable option to the proper recovery methods.
Abstract: The prospective function of a novel energy efficient fermentation technology has been getting great attention in the past fifty years due to the quick raise in petroleum costs. Fermentation chemicals are still limited in the modern market in huge part because of trouble in recovery of carboxylic acids. Therefore, it is needed considerable development in the current recovery technology. Carboxylic acids have been used as the majority of fermentation chemicals. This paper presents a state-of-the-art review on the reactive extraction of carboxylic acids from fermentation broths. This paper principally focuses on reactive extraction that is found to be a capable option to the proper recovery methods.

100 citations

Journal ArticleDOI
TL;DR: Interest in pyruvic acid has been growing due to the increase in its potential areas of use and its importance in metabolic reactions as mentioned in this paper, however, the limitations on recovery have prom
Abstract: Interest in pyruvic acid has been growing due to the increase in its potential areas of use and its importance in metabolic reactions. These reasons along with the limitations on recovery have prom...

64 citations

Journal ArticleDOI
TL;DR: In this paper, the effects of conditions of fermentation broth on the extraction kinetics were investigated using a microporous membrane-based stirred cell for the extraction of succinic acid with tri-n -octylamine.

62 citations