Youqing Shen

TL;DR: An overview of recent developments in nanomedicine is provided and the current challenges and upcoming opportunities for the field are highlighted and translation to the clinic is highlighted.

TL;DR: The typical cancer‐drug‐delivery process of an intravenously administered nanomedicine is analyzed and it is concluded that the delivery involves a five‐step CAPIR cascade and that high efficiency at every step is critical to guarantee high overall therapeutic efficiency.

TL;DR: The micelle's blood circulation time and tumor accumulation increased with the increase in their diameters, with optimal diameter range of 100 to 160 nm, but the much higher tumor accumulation of the large micelles did not result in significantly improved therapeutic efficacy, because the large mouselles had poorer tumor penetration than the small ones.

TL;DR: The concept directly using drugs as part of a carrier is applicable to fabricating other highly efficient nanocarriers with a substantially reduced use of inert carrier materials and increased drug loading content without premature burst release.

TL;DR: A new type of "task specific ionic liquid" was synthesized by the reaction of tetrabutylphosphonium hydroxide with amino acids, including glycine, L-alanine, T(C4)4][AA), and no changes in absorption capacity and kinetics were found after four cycles of absorption/desorption.