Y
Yu Feng
Researcher at Oklahoma State University–Stillwater
Publications - 125
Citations - 18217
Yu Feng is an academic researcher from Oklahoma State University–Stillwater. The author has contributed to research in topics: Antibody & Heat transfer. The author has an hindex of 35, co-authored 95 publications receiving 16791 citations. Previous affiliations of Yu Feng include Jilin University & National Institutes of Health.
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Journal ArticleDOI
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor
TL;DR: A cofactor for HIV-1 (human immunodeficiency virus-type 1) fusion and entry was identified with the use of a novel functional complementary DNA (cDNA) cloning strategy that is a putative G protein-coupled receptor with seven transmembrane segments.
Journal Article
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein–Coupled Receptor
TL;DR: Fusin this article is a putative G protein-coupled receptor with seven transmembrane segments, which enabled CD4-expressing nonhuman cell types to support HIV-1 Env-mediated cell fusion and infection.
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CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1
Ghalib Alkhatib,Christophe Combadiere,Christopher C. Broder,Yu Feng,Paul E. Kennedy,Philip Murphy,Edward A. Berger +6 more
TL;DR: Recombinant CC CKR5, a G protein-coupled receptor for these chemokines, rendered CD4-expressing nonhuman cells fusion-competent preferentially with macrophage-tropic Envs, and is thus a fusion cofactor for HIV-1 strains.
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Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
Xueling Wu,Zhi Yong Yang,Yuxing Li,Carl Magnus Hogerkorp,William R. Schief,Michael S. Seaman,Tongqing Zhou,Stephen D. Schmidt,Lan Wu,Ling Xu,Nancy S. Longo,Krisha McKee,Sijy O'Dell,Mark K. Louder,Diane Wycuff,Yu Feng,Martha Nason,Nicole A. Doria-Rose,Mark Connors,Peter D. Kwong,Mario Roederer,Richard T. Wyatt,Gary J. Nabel,John R. Mascola +23 more
TL;DR: Three broadly neutralizing antibodies are identified, isolated from an HIV-1–infected individual, that exhibited great breadth and potency of neutralization and were specific for the co-receptor CD4-binding site of the glycoprotein 120 (gp120), part of the viral Env spike.
Journal ArticleDOI
Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals.
Ling Ni,Fang Ye,Meng Li Cheng,Yu Feng,Yong Qiang Deng,Hui Zhao,Peng Wei,Jiwan Ge,Mengting Gou,Xiaoli Li,Lin Sun,Tian-Shu Cao,Pengzhi Wang,Chao Zhou,Rong-Rong Zhang,Peng Liang,Han Guo,Xinquan Wang,Cheng-Feng Qin,Fang Chen,Chen Dong +20 more
TL;DR: Blood from COVID-19 patients who have recently become virus-free and therefore were discharged was collected, and SARS-CoV-2-specific humoral and cellular immunity in 8 newly discharged patients was detected, and there was a strong correlation between neutralization antibody titers and the numbers of virus-specific T cells.