Yu Fu

TL;DR: Using genetic engineering in mice, approximately 20 Cre and inducible CreER knockin driver lines that reliably target major classes and lineages of GABAergic neurons are generated, thereby enabling a systematic and comprehensive analysis from cell fate specification, migration, and connectivity, to their functions in network dynamics and behavior.

TL;DR: These findings establish a cortical circuit for the enhancement of visual response by locomotion and provide a potential common Circuit for the modulation of sensory processing by behavioral state.

TL;DR: This work demonstrates a novel function of GABA in regulating GABAergic innervation in the adolescent brain, when GABA is mainly known as an inhibitory transmitter and implicates GAD67-mediated GABA synthesis in activity-dependent regulation of inhibitory innervation patterns.

TL;DR: Using a real-time gene expression system, differences in the kinetics of transcriptional activation between interphase and post-mitotic cells that are mediated by a chromatin-based epigenetic mechanism are identified.

TL;DR: It is shown that polysialic acid (PSA), presented by the neural cell adhesion molecule, has a role in the maturation of GABAergic innervation and ocular dominance plasticity.