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Yu Huang

Bio: Yu Huang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Materials science. The author has an hindex of 136, co-authored 1492 publications receiving 89209 citations. Previous affiliations of Yu Huang include The Chinese University of Hong Kong & Samsung.


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TL;DR: In this article, the authors examined the antioxidant activity of heane, acetone, and methanol extracts, as well as Baicalein purified from the dry roots of Scutellaria baicalensis Georgi (common name: Huangqin), in heated canola oil.
Abstract: There is an increasing interest in natural antioxidants present in traditional Chinese herbal medicines. The present study examined the antioxidant activity of heane, acetone, and methanol extracts, as well as baicalein purified from the dry roots of Scutellaria baicalensis Georgi (common name: Huangqin), in heated canola oil. Oxygen consumption and decreases in linoleic acid linolenic acid content were monitored in canola oil held at 90–93°C. Among the three extracts, the acetone extract was most effective against oxidation of canola oil, followed by the methanol extract of the dry roots. The antioxidant activity of these three extracts correlated well with their content of baicalein, which provided strong protection to canola oil from oxidation. The antioxidant activity of Huangqin acetone extract was dose-dependent. The acetone extract at 100 ppm or above was even more effective than butylated hydroxytoluene at 200 ppm in protecting canola oil from oxidation. The present results suggest that the acetone extract of these roots should be further explored as a potential source of natural antioxidants for use in the processed foods.

25 citations

Journal ArticleDOI
TL;DR: The present study has provided the first line of evidence suggesting the long-term beneficial effects of estrogen and tamoxifen therapy on vascular ion channel expressions, which may be an important mechanism by which the favorable modulation of vessel tone by estrogen or selective estrogen receptor modulators is mediated.

25 citations

Journal ArticleDOI
TL;DR: In this paper, a magnetically controlled laser induced plasma micro-machining (MC-LIPMM) was proposed to improve the machining characteristics of silicon materials and cavitation bubbles showed an apparently negative impact on the surface morphology.

25 citations

Journal ArticleDOI
TL;DR: This assay was successfully applied to the determination of CAP in spiked environmental water samples and has a wide scope in that it may be applied to a wide range of analytes if respective aptamers are available.
Abstract: A competitive colorimetric assay has been established to detect chloramphenicol (CAP). It is based on the use of colloidal and electrostatically stabilized aptamer-modified gold nanoparticles (GNPs). The CAP aptamer is modified by a sequence of 5 adenosine groups to anchor it on the surface of GNPs. It can competitively capture two compounds, viz. D-(-)-threo-2-amino-1-(4-nitrophenyl)-1,3-propanediol (CAP-base, with a positive charge) and CAP (which is uncharged). The capture of the positively charged CAP-base triggers the aggregation of modified GNPs in salt-containing solution, and this causes a color change from red to purple. However, in the presence of CAP and CAP-base, the capture of the uncharged CAP weakens this color change by a competing process for capture. Thus, the concentration of CAP is associated with the degree of deaggregation of GNPs and can be quantified by the ratio of absorbances at 620 nm and 520 nm. The assay has a 22 nM limit of detection in acidic solution, and the response is linear in the range of 0.20 to 3.20 μM CAP concentration. This assay was successfully applied to the determination of CAP in spiked environmental water samples. Conceivably, this method has a wide scope in that it may be applied to a wide range of analytes if respective aptamers are available.

25 citations

Journal ArticleDOI
TL;DR: A demonstration unit for the solar-assisted large-scale cleaning system (SALSCS), with a solar collector 43 × 60 m2 and a tower 60 m in height, was built in Xi'an, China, to study its effectiveness in terms of urban air pollution remediation.
Abstract: A demonstration unit for the Solar-Assisted Large-Scale Cleaning System (SALSCS), with a solar collector 43 × 60 m2 in horizontal dimensions and a tower 60 m in height, was built in Xi’an, China, to study its effectiveness in terms of urban air pollution remediation To simulate an urban-scale SALSCS with dimensions ranging 10–120 m that was proposed for installation on urban blocks, we first performed experimental measurements on the demonstration unit and used the experimental data to validate a numerical model that we developed This paper presents the field measurements conducted during three days in Jan 2017 in Xi’an The experimental and numerical results of the system flow rate and temperature showed good agreement for six of the eight measurement cases, with average discrepancies of 163 m3 s–1 for the flow rate and 078°C for the temperature Larger discrepancies for the other two cases were observed, and the reasons were analyzed During the measurements, the filtration efficiency of the filter media installed in the north section of the system with regard to PM25 was evaluated to be 735% The validated numerical model was applied to study the performance characteristics of the urban-scale SALSCS, and these results will be presented in Part II

25 citations


Cited by
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08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

33,785 citations

01 May 1993
TL;DR: Comparing the results to the fastest reported vectorized Cray Y-MP and C90 algorithm shows that the current generation of parallel machines is competitive with conventional vector supercomputers even for small problems.
Abstract: Three parallel algorithms for classical molecular dynamics are presented. The first assigns each processor a fixed subset of atoms; the second assigns each a fixed subset of inter-atomic forces to compute; the third assigns each a fixed spatial region. The algorithms are suitable for molecular dynamics models which can be difficult to parallelize efficiently—those with short-range forces where the neighbors of each atom change rapidly. They can be implemented on any distributed-memory parallel machine which allows for message-passing of data between independently executing processors. The algorithms are tested on a standard Lennard-Jones benchmark problem for system sizes ranging from 500 to 100,000,000 atoms on several parallel supercomputers--the nCUBE 2, Intel iPSC/860 and Paragon, and Cray T3D. Comparing the results to the fastest reported vectorized Cray Y-MP and C90 algorithm shows that the current generation of parallel machines is competitive with conventional vector supercomputers even for small problems. For large problems, the spatial algorithm achieves parallel efficiencies of 90% and a 1840-node Intel Paragon performs up to 165 faster than a single Cray C9O processor. Trade-offs between the three algorithms and guidelines for adapting them to more complex molecular dynamics simulations are also discussed.

29,323 citations

28 Jul 2005
TL;DR: PfPMP1)与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

18,940 citations