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Yu Sun

Researcher at Huazhong University of Science and Technology

Publications -  104
Citations -  3653

Yu Sun is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Hearing loss. The author has an hindex of 24, co-authored 90 publications receiving 2681 citations. Previous affiliations of Yu Sun include Tianjin University & Emory University.

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Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study.

TL;DR: It is found that digestive symptoms are common in patients with COVID-19 and that the index of suspicion may need to be raised earlier in at-risk patients presenting with digestive symptoms, but further large sample studies are needed to confirm these findings.
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A safe, simple and efficient doxorubicin prodrug hybrid micelle for overcoming tumor multidrug resistance and targeting delivery.

TL;DR: A pH-sensitive prodrug was introduced by conjugating anticancer drug, doxorubicin (DOX), onto d-α-tocopherol polyethylene glycol 1000 succinate (TPGS) via a cleavable Schiff base linkage to form a simple but multifunctional hybrid micelle system, which can realize high drug loading capability and biocompatibility.
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The nuclear transcription factor FoxG1 affects the sensitivity of mimetic aging hair cells to inflammation by regulating autophagy pathways.

TL;DR: FoxG1 affects the sensitivity of mimetic aging hair cells to inflammation by regulating autophagy pathways, and this study finds that cell death and apoptosis were significantly increased after LPS injury.
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Targeted connexin26 ablation arrests postnatal development of the organ of Corti

TL;DR: It is demonstrated that Cx26 plays essential roles in postnatal maturation and homoeostasis of the organ of Corti before the onset of hearing.
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Connexin30 null and conditional connexin26 null mice display distinct pattern and time course of cellular degeneration in the cochlea

TL;DR: This study revealed that cellular degeneration in the cochlea of cCx26 null mice was dramatically more rapid and widespread than that observed in Cx30 null mice, suggesting heterogeneous underlying deafness mechanisms.