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Yuanyuan Xu
Researcher at China Medical University (PRC)
Publications - 64
Citations - 1971
Yuanyuan Xu is an academic researcher from China Medical University (PRC). The author has contributed to research in topics: Arsenic & Oxidative stress. The author has an hindex of 22, co-authored 64 publications receiving 1461 citations. Previous affiliations of Yuanyuan Xu include Research Triangle Park & National Institutes of Health.
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Journal ArticleDOI
The Role of Reactive Oxygen Species in Arsenic Toxicity.
TL;DR: The pathways involved in arsenic-induced redox imbalance are detailed, as well as current studies on prophylaxis and treatment strategies using antioxidants.
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Urinary arsenic metabolites in children and adults exposed to arsenic in drinking water in Inner Mongolia, China.
TL;DR: Children had higher a capacity for secondary methylation of As than adults when exposed to the same concentrations of iAs in drinking water, and exposure to As may increase the capacity for methylation in children to some extent.
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An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy.
Jiayu Zhu,Huihui Wang,Feng Chen,Jingqi Fu,Yuanyuan Xu,Yongyong Hou,Henry H. Kou,Cheng Zhai,M. Bud Nelson,Qiang Zhang,Melvin E. Andersen,Jingbo Pi +11 more
TL;DR: The possible Nrf2-inhibiting mechanisms of these compounds, their effects sensitizing cancer cells to chemotherapeutic agents, and the prospect of applying them in clinical cancer therapy are enumerated.
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Arsenic speciation transported through the placenta from mother mice to their newborn pups
Yaping Jin,Shuhua Xi,Xin Li,Chunwei Lu,Gexin Li,Yuanyuan Xu,Chun-Qing Qu,Yu-Hong Niu,Guifan Sun +8 more
TL;DR: The primary goal of the present study was to confirm the arsenic species that can be transferred from the mother to the bodies of newborn pups through the placenta and the speciated arsenic distribution in the liver and brain of newborn mice after gestational maternal exposure to inorganic arsenic (iAs).
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Association of oxidative stress with arsenic methylation in chronic arsenic-exposed children and adults.
TL;DR: Blood GSH levels and urinary 8-OHdG concentrations of arsenic-exposed children and adults showed strong associations with the levels of urinary arsenic species, and associations of arsenic methylation capacity with 8- OHdG, GSH and SOD were observed in multivariate regression analyses.