Y
Yukun Chen
Researcher at Vanderbilt University
Publications - 23
Citations - 2830
Yukun Chen is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Active learning (machine learning) & Named-entity recognition. The author has an hindex of 16, co-authored 22 publications receiving 2455 citations.
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Wisdom of crowds for robust gene network inference
Daniel Marbach,James C. Costello,Robert Küffner,Nicole M. Vega,Robert J. Prill,Diogo M. Camacho,Kyle R. Allison,Andrej Aderhold,Richard Bonneau,Yukun Chen,James J. Collins,Francesca Cordero,Martin Crane,Frank Dondelinger,Mathias Drton,Roberto Esposito,Rina Foygel,Alberto de la Fuente,Jan Gertheiss,Pierre Geurts,Alex Greenfield,Marco Grzegorczyk,Anne-Claire Haury,Benjamin Holmes,Torsten Hothorn,Dirk Husmeier,Vân Anh Huynh-Thu,Alexandre Irrthum,Manolis Kellis,Guy Karlebach,Sophie Lèbre,Vincenzo De Leo,Aviv Madar,Subramani Mani,Fantine Mordelet,Harry Ostrer,Zhengyu Ouyang,Ravi Pandya,Tobias Petri,Andrea Pinna,Christopher S. Poultney,Serena Rezny,Heather J. Ruskin,Yvan Saeys,Ron Shamir,Alina Sîrbu,Mingzhou Song,Nicola Soranzo,Alexander Statnikov,Gustavo Stolovitzky,Nicci Vega,Paola Vera-Licona,Jean-Philippe Vert,Alessia Visconti,Haizhou Wang,Louis Wehenkel,Lukas Windhager,Yang Zhang,Ralf Zimmer +58 more
TL;DR: A comprehensive blind assessment of over 30 network inference methods on Escherichia coli, Staphylococcus aureus, Saccharomyces cerevisiae and in silico microarray data defines the performance, data requirements and inherent biases of different inference approaches, and provides guidelines for algorithm application and development.
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A study of machine-learning-based approaches to extract clinical entities and their assertions from discharge summaries.
TL;DR: Systematic evaluation on the training set showed that Conditional Random Fields outperformed Support Vector Machines, and semantic information from existing natural-language-processing systems largely improved performance, although contributions from different types of features varied.
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Large-scale prediction of adverse drug reactions using chemical, biological, and phenotypic properties of drugs
Mei Liu,Yonghui Wu,Yukun Chen,Jingchun Sun,Zhongming Zhao,Xue-wen Chen,Michael E. Matheny,Hua Xu +7 more
TL;DR: A machine-learning-based approach for ADR prediction by integrating the phenotypic characteristics of a drug, including indications and other known ADRs, with the drug's chemical structures and biological properties, including protein targets and pathway information is proposed.
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Medical decision support using machine learning for early detection of late-onset neonatal sepsis.
Subramani Mani,Asli Ozdas,Constantin F. Aliferis,Huseyin Atakan Varol,Qingxia Chen,Randy J. Carnevale,Yukun Chen,Joann Romano-Keeler,Hui Nian,Jörn-Hendrik Weitkamp +9 more
TL;DR: Predictive models developed from off-the-shelf and EMR data using machine learning (ML) algorithms exceeded the treatment sensitivity and treatment specificity of clinicians.
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A study of active learning methods for named entity recognition in clinical text
TL;DR: In the simulated setting, AL methods, particularly uncertainty-sampling based approaches, seemed to significantly save annotation cost for the clinical NER task.