Y
Yung Hyun Choi
Researcher at Dong-eui University
Publications - 769
Citations - 18945
Yung Hyun Choi is an academic researcher from Dong-eui University. The author has contributed to research in topics: Apoptosis & Protein kinase B. The author has an hindex of 62, co-authored 700 publications receiving 15859 citations. Previous affiliations of Yung Hyun Choi include UPRRP College of Natural Sciences.
Papers
More filters
Journal ArticleDOI
Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells
Hye Young Park,Min Ho Han,Cheol Park,Cheng-Yun Jin,Gi-Young Kim,Il-Whan Choi,Nam Deuk Kim,Taek-Jeong Nam,Taeg Kyu Kwon,Yung Hyun Choi +9 more
TL;DR: The inhibitory effects of fucoidan on production of lipopolysaccharide (LPS)-induced pro-inflammatory mediators in BV2 microglia are investigated to suggest thatfucoidan may offer substantial therapeutic potential for treatment of neurodegenerative diseases that are accompanied by microglial activation.
Journal ArticleDOI
Involvement of Autophagy in Oncogenic K-Ras-induced Malignant Cell Transformation
Min Jung Kim,Soo Jung Woo,Chang Hwan Yoon,Jae-Seong Lee,Sungkwan An,Yung Hyun Choi,Sang-Gu Hwang,Gyesoon Yoon,Su Jae Lee +8 more
TL;DR: Novel evidence is provided that autophagy is critically involved in malignant transformation by oncogenic K-Ras and shows that reactive oxygen species-mediated JNK activation plays a causal role in Autophagy induction through up-regulation of ATG5 and ATG7.
Journal ArticleDOI
Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis.
Mei Jing Piao,Mee Jung Ahn,Kyoung Ah Kang,Yea Seong Ryu,Yu Jae Hyun,Kristina Shilnikova,Ao Xuan Zhen,Jin Woo Jeong,Yung Hyun Choi,Hee Kyoung Kang,Young Sang Koh,Jin Won Hyun +11 more
TL;DR: The results indicate that PM2.5 induced oxidative stress by generating reactive oxygen species both in vitro and in vivo, which led to DNA damage, lipid peroxidation, and protein carbonylation, and caused apoptosis in HaCaT cells and mouse skin tissue.
Journal ArticleDOI
Anti-inflammatory effects of β-lapachone in lipopolysaccharide-stimulated BV2 microglia
TL;DR: The results show that LAPA may be useful as a potential anti-inflammatory agent for attenuating inflammatory diseases.
Journal ArticleDOI
Rosmarinic acid sensitizes cell death through suppression of TNF-α-induced NF-κB activation and ROS generation in human leukemia U937 cells
TL;DR: It is found that RA treatment significantly sensitizes TNF-alpha-induced apoptosis in human leukemia U937 cells through the suppression of nuclear transcription factor-kappaB (NF- kappaB) and reactive oxygen species (ROS).