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Yuri L. Lyubchenko
Researcher at University of Nebraska Medical Center
Publications - 251
Citations - 10629
Yuri L. Lyubchenko is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: DNA & DNA supercoil. The author has an hindex of 56, co-authored 239 publications receiving 9661 citations. Previous affiliations of Yuri L. Lyubchenko include Arizona State University & Russian Academy of Sciences.
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Visualization of supercoiled DNA with atomic force microscopy in situ
TL;DR: The AFM data show that at low ionic strength, DNA molecules are loosely interwound supercoils with an irregular shape and that overall geometry of supercoiled DNA depends dramatically on ionic conditions.
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Adsorption of DNA to mica, silylated mica, and minerals : characterization by atomic force microscopy
Magdalena Bezanilla,S. Manne,S. Manne,S. Manne,Daniel E. Laney,Yuri L. Lyubchenko,Yuri L. Lyubchenko,Yuri L. Lyubchenko,Helen G. Hansma +8 more
TL;DR: A comparison of DNA adsorption from different buffers onto mica and silylated mica shows that buffer composition is much less important for DNA ads orption to silylation mica, and suggests that for good adsorptive DNA must be electrostatically adsorbed to the surface.
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Atomic force microscopy of long DNA: imaging in air and under water
TL;DR: Stark atomic force microscopy images of the intact lambda bacteriophage genome and of several lambda restriction fragments both in air and under water are obtained, using a process for binding unmodified double-stranded DNA to chemically treated mica surfaces.
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Silatrane-based surface chemistry for immobilization of DNA, protein-DNA complexes and other biological materials.
Luda S. Shlyakhtenko,Alexander A. Gall,Alexander Filonov,Zoran Cerovac,Alexander Y. Lushnikov,Yuri L. Lyubchenko +5 more
TL;DR: The results are consistent with a diffusion controlled mechanism suggesting that DNA molecules bind irreversibly with the surface upon immobilization, and it is demonstrated directly that the segments of DNA molecules could move along the surface if the sample is imaged in aqueous solution without drying of the sample.
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Simple test system for single molecule recognition force microscopy
Christian K. Riener,Cordula M. Stroh,Andreas Ebner,Christian W. Klampfl,A. A. Gall,Christoph Romanin,Yuri L. Lyubchenko,Peter Hinterdorfer,Hermann J. Gruber +8 more
TL;DR: An easy-to-use test system for detecting receptor–ligand interactions on the single molecule level using atomic force microscopy (AFM) and it is concluded that this system is well suited as calibration or start-up kit for single molecule recognition force microscopeopy.